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A3913

Sigma-Aldrich

L-Argininamide dihydrochloride

≥98%, suitable for ligand binding assays

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About This Item

Formula empirica (notazione di Hill):
C6H15N5O · 2HCl
Numero CAS:
14975-30-5
Peso molecolare:
246.14
Numero MDL:
MFCD00058286
Codice UNSPSC:
12352209
ID PubChem:
24890827
NACRES:
NA.26
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Nome del prodotto

L-Argininamide dihydrochloride,

Saggio

≥98%

Livello qualitativo

200

Stato

powder

tecniche

ligand binding assay: suitable

Colore

white to off-white

Temperatura di conservazione

−20°C

Stringa SMILE

Cl.N[C@@H](CCCNC(N)=N)C(N)=O

InChI

1S/C6H15N5O.ClH/c7-4(5(8)12)2-1-3-11-6(9)10;/h4H,1-3,7H2,(H2,8,12)(H4,9,10,11);1H/t4-;/m0./s1
BPQLYFCEVVKLLX-WCCKRBBISA-N

Applicazioni

L-Argininamide dihydrochloride has been used as an additive to compare its effect over L-arg in egg lysozyme refolding studies.[1] It has also been used as a component of substrate stock solution for enzymatic kyotorphin synthesis.[2]

Azioni biochim/fisiol

L-Argininamide (L-Arm) is a hydrophilic amino acid derivative[2] that is used as a model compound in physicochemical characteristic studies of ligand binding DNA aptamers and their potential development as fluorescent aptasensors.[3]

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H302,H370

Classi di pericolo

Acute Tox. 4 Oral - STOT SE 1

Organi bersaglio

Eyes

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
BCCK8934
BCCF9587
BCBV9948
BCBQ1412V
BCBQ1412

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Levitsky et al.
Enzyme and microbial technology, 26(8), 608-613 (2000-05-04)
Design of enzymatic kyotorphin synthesis in low water media has been carried out as a function of enzyme nature, the immobilization support material and the reaction medium, by using N-benzoyl-L-tyrosine ethyl ester and L-argininamide as substrates. Native and chemically-glycated alpha-chymotrypsin
RNA dynamics by design: biasing ensembles towards the ligand-bound state.
Andrew C Stelzer et al.
Angewandte Chemie (International ed. in English), 49(33), 5731-5733 (2010-06-29)
Qi Zhang et al.
Science (New York, N.Y.), 311(5761), 653-656 (2006-02-04)
Using a domain elongation strategy, we decoupled internal motions in RNA from overall rotational diffusion. This allowed us to site-specifically resolve a manifold of motional modes in two regulatory RNAs from HIV-1 with the use of nuclear magnetic resonance spin
Zece Zhu et al.
Chemical communications (Cambridge, England), 47(11), 3192-3194 (2011-01-29)
The nucleic acid minor groove binding dyes, DAPI and Hoechst 33258, were for the first time used in label-free aptamer-based sensors for L-argininamide. The synergy binding effect results in the enhancement of fluorescence of dyes. The method for detection of
G Reid Bishop et al.
Biophysical chemistry, 126(1-3), 165-175 (2006-08-18)
The thermal stability and ligand binding properties of the L-argininamide-binding DNA aptamer (5'-GATCGAAACGTAGCGCCTTCGATC-3') were studied by spectroscopic and calorimetric methods. Differential calorimetric studies showed that the uncomplexed aptamer melted in a two-state reaction with a melting temperature T(m)=50.2+/-0.2 degrees C
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