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T4626

Sigma-Aldrich

Nα-p-Tosyl-L-arginine methyl ester hydrochloride

≥98% (TLC), suitable for ligand binding assays

Sinonimo/i:

TAME hydrochloride

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About This Item

Formula condensata:
H2NC(=NH)NH(CH2)3CH(NHSO2C6H4CH3)CO2CH3 · HCl
Numero CAS:
Peso molecolare:
378.87
Beilstein:
3922357
Numero CE:
Numero MDL:
Codice UNSPSC:
12352103
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.26

product name

Nα-p-Tosyl-L-arginine methyl ester hydrochloride,

Saggio

≥98% (TLC)

Forma fisica

powder

tecniche

ligand binding assay: suitable

Colore

white

Punto di fusione

145-147 (lit.)

Temperatura di conservazione

−20°C

Stringa SMILE

Cl.COC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1ccc(C)cc1

InChI

1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1
JIQFFACVQXXHMY-YDALLXLXSA-N

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Applicazioni

Nα-p-Tosyl-L-arginine methyl ester hydrochloride has been used as an esterolytic substrate to assess trypsin-like activity in midgut extracts. It has also been used as a substrate for measuring trypsin activity of pancreatin and human intestinal samples.

Azioni biochim/fisiol

Nα-p-Tosyl-L-arginine methyl ester (TAME) binds to anaphase-promoting complex (APC) and prevents its activation by Cdc20 and Cdh1.

Substrati

Substrate for trypsin, thrombin, plasmin, and other proteases.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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