D6750

Desossicolato di sodio

≥97% (titration)

• Sinonimo/i: Acido 3α,12α-diidrossi-5β-colanico, Acido 7-desossicolico, Acido desossicolico
• Formula empirica (notazione di Hill): C₂₄H₃₉NaO₄
• Numero CAS: 302-95-4
• Peso molecolare: 414.55
• Beilstein: 3581950
• Numero CE: 206-132-7
• Numero MDL: MFCD00064139
• Codice UNSPSC: 12161900
• ID PubChem: 24894044
• NACRES: NA.21

Proprietà

• Descrizione: anionic
• Livello qualitativo: 200
• Saggio: ≥97% (titration)
• Forma fisica: powder
• PM: micellar avg mol wt 1200-5000
• Numero d'aggregazione: 3-12
• CMC: 2-6 mM (20-25°C)
• Solubilità: water: 50 mg/mL, clear, colorless to light yellow
• HLB: 16
• Gruppo funzionale: carboxylic acid
• Condizioni di spedizione: ambient
• Temperatura di conservazione: room temp
• Stringa SMILE: [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
• InChI: 1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1; FHHPUSMSKHSNKW-SMOYURAASA-M

Descrizione

Descrizione generale

Deoxycholic acid sodium salt, also known as Sodium Deoxycholate, is a highly versatile ionic detergent utilized for its exceptional ability to solubilize membrane-bound proteins and lyse cells. Its mechanism involves disrupting cell membranes and dissolving hydrophobic molecules, making it an invaluable reagent in scientific research applications. In protein research, it plays a pivotal role in solubilizing proteins, particularly those embedded in membranes, enabling their extraction, purification, and subsequent analysis.

Moreover, Sodium Deoxycholate extends its utility to nucleic acid extraction from cells and tissues. By lysing cells and disrupting cellular structures, it facilitates the release and purification of nucleic acids, proving valuable in cell biology and biochemical research. Beyond these applications, its effectiveness in cell lysis processes positions it as a valuable tool for breaking down cells and releasing their contents, finding applications in diverse biological studies, encompassing microscopy, cell biology, and biochemical research.

Applicazioni

Sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue. It has been used in the decellularization of aortic valvular conduit.

Azioni biochim/fisiol

Solubilizes fats for absorption in the intestines.

Caratteristiche e vantaggi

Highly versatile surfactant for your cell biology and biochemical research

Altre note

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302
• Consigli di prudenza: P264 - P270 - P301 + P312 - P501
• Classi di pericolo: Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves