This product is also soluble in water at 10mg/ml. Please see the link below to review the product datasheet:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/195/258/p4020pis.pdf
P4020
Protamine sulfate
amorphous powder
Sinonimo/i:
Salmine, Salmine from salmon
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1 G
CHF 57.00
5 G
CHF 93.80
10 G
CHF 233.00
25 G
CHF 432.00
100 G
CHF 1’440.00
Scegli un formato
Cambia visualizzazione
1 G
CHF 57.00
5 G
CHF 93.80
10 G
CHF 233.00
25 G
CHF 432.00
100 G
CHF 1’440.00
About This Item
Prodotti consigliati
Nome del prodotto
Protamine sulfate salt from salmon, Grade X, amorphous powder
Tipo
Grade X
Stato
amorphous powder
Impurezze
histone, free (Millon test)
Colore
white to off-white
Solubilità
6 M HCl: 25 mg/mL
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Descrizione generale
Applicazioni
May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Azioni biochim/fisiol
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Are there other solvents besides 6M HCl to bring protamine sulfate salt into solution?
1 answer-
Helpful?
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Bonjour, Pourriez vous me confirmer qu'il s'agit bien d'un polypeptide et de combien d'unité de monomère est il formé ? Pourriez vous m'envoyer la représentation de la molécule ? merci
1 answer-
Unfortunately, structural studies on for this product have not been performed. However, regarding structure characterization and molecular representation of protamine from salmon, the following publication may be of interest for reference.
J Biol Chem. 1959 Sep:234:2314-6.
Physical and chemical properties of protamine from the sperm of salmon (Oncorhynchus tschawytscha). II. Anion binding characteristics
https://pubmed.ncbi.nlm.nih.gov/13807973/Helpful?
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