The solubility of this product is tested in chloroform at 50 mg/mL. Solution stability has not been determined, however the acetate form is unstable in solution and should be prepared fresh. The end user would have to validate solution stability of this compound experimentally. The NIH lists the material as being soluble in ethanol, methanol, ether, and acetone. Please see the link below to review this publication:
https://pubchem.ncbi.nlm.nih.gov/compound/Medroxyprogesterone#section=Color-Form
M6013
Medroxyprogesterone
Sinonimo/i:
17α-Hydroxy-6α-methyl-4-pregnene-3,20-dione, 17α-Hydroxy-6α-methylprogesterone, 6α-Methyl-5-pregnen-17α-ol-3,20-dione, 6-Dihydromegestrol
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About This Item
Formula empirica (notazione di Hill):
C22H32O3
Numero CAS:
Peso molecolare:
344.49
Beilstein:
2510965
Numero CE:
Numero MDL:
Codice UNSPSC:
51111800
ID PubChem:
NACRES:
NA.77
Prezzi e disponibilità al momento non sono disponibili
Prodotti consigliati
Origine biologica
synthetic (organic)
Saggio
≥98% (HPLC)
Stato
powder
Solubilità
chloroform: 50 mg/mL, clear, colorless to faintly yellow
Condizioni di spedizione
ambient
Temperatura di conservazione
room temp
Stringa SMILE
[H][C@@]12C[C@H](C)C3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(C)=O
InChI
1S/C22H32O3/c1-13-11-16-17(20(3)8-5-15(24)12-19(13)20)6-9-21(4)18(16)7-10-22(21,25)14(2)23/h12-13,16-18,25H,5-11H2,1-4H3/t13-,16+,17-,18-,20+,21-,22-/m0/s1
FRQMUZJSZHZSGN-HBNHAYAOSA-N
Informazioni sul gene
rat ... Ar(24208)
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Avvertenza
Much of the pharmacology literature refers to medroxyprogesterone acetate as medroxyprogesterone, but they are of course not the same substance.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Repr. 2
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Dispositivi di protezione individuale
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Adarsh J Sai et al.
Menopause (New York, N.Y.), 18(10), 1101-1112 (2011-06-30)
The aim of this study was to examine the effect of conjugated equine estrogens alone (ET), conjugated equine estrogens + medroxyprogesterone (EPT), calcitriol alone, calcitriol + EPT/ET, or placebo on serum lipid profile and analyze the interaction with estrogen receptor-α
Clinical significance of differences in bioavailability of medroxyprogesterone acetate preparations.
A D Stockdale et al.
Clinical pharmacokinetics, 16(3), 129-133 (1989-03-01)
M F Fung et al.
Obstetrics and gynecology, 78(6), 1033-1038 (1991-12-01)
We conducted a retrospective review of 44 patients with metastatic or recurrent endometrial carcinoma treated with cisplatin, doxorubicin, cyclophosphamide, and medroxyprogesterone acetate. Thirty-six women had metastatic disease; eight had recurrent disease. In the metastatic group, 12 women had positive peritoneal
The role of medroxyprogesterone acetate (MPA) in the treatment of renal adenocarcinoma.
M Kjaer
Cancer treatment reviews, 15(3), 195-209 (1988-09-01)
Kevin D Beck et al.
Neurobiology of learning and memory, 97(1), 148-155 (2011-12-06)
Ovarian hormones modulate acquisition processes involved in classical conditioning. Although progesterone has been indirectly implicated, its role in classical conditioning of the eyeblink response has not been directly investigated. We assessed the effects of daily dosing of progesterone or medroxyprogesterone
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is there is any other solution can be used to dissolve the Medroxyprogesterone and whats the tempreture we need to use for stoarge after dissolving the Medroxyprogesterone
1 answer-
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