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M3778

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

Name: N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride
Brand: SIGMA
Price: 166 CHF

≥97% (GC), MAO-A inhibitor, powder

Sinonimo/i:

Clorgyline

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Taglio della confezione	Disponibilità	Prezzo
50 mg	Per conoscere la disponibilità, visualizza il carrello	CHF 166.00
100 mg	Per conoscere la disponibilità, visualizza il carrello	CHF 202.00
500 mg	Per conoscere la disponibilità, visualizza il carrello	CHF 629.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₃H₁₅Cl₂NO · HCl

Numero CAS:

17780-75-5

Peso molecolare:

308.63

NACRES:

NA.77

PubChem Substance ID:

24278179

UNSPSC Code:

12352116

EC Number:

241-760-5

MDL number:

MFCD00052012

Assay:

≥97% (GC)

Form:

powder

CHF 166.00

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Proprietà

Nome del prodotto

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride, ≥97% (GC)

Quality Segment

100

assay

≥97% (GC)

form

powder

solubility

DMSO: 10 mg/mL, clear, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

Cl.CN(CCCOc1ccc(Cl)cc1Cl)CC#C

InChI

1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H

InChI key

BBAZDLONIUABKI-UHFFFAOYSA-N

Gene Information

human ... MAOA(4128)
rat ... Maoa(29253), Maob(25750)

Descrizione

Application

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride has been used as a monoamine oxidase A (MAO-A) inhibitor:

in MAO-A biochemical assay[1]
to study its effects on the transit of serotonin (5-HT) in the human placenta explants[2]
to study its effects on human prostate cancer cells[3]

Biochem/physiol Actions

MAO-A inhibitor.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Questo articolo	P8511	A3085	T3146
Sigma-Aldrich M3778 N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride	Sigma-Aldrich P8511 trans-2-Phenylcyclopropylamine hydrochloride	Sigma-Aldrich A3085 5-(N-Ethyl-N-isopropyl)amiloride	Sigma-Aldrich T3146 Trimipramine maleate salt
assay ≥97% (GC)	assay ≥97% (TLC)	assay ≥98% (TLC)	assay ≥98% (TLC)
form powder	form powder	form powder	form powder
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 200
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
solubility DMSO: 10 mg/mL, clear, colorless to faintly yellow	solubility ethanol: 50 mg/mL, clear to slightly hazy	solubility methanol: 9.80-10.20 mg/mL, clear, light yellow to yellow	solubility chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow
Gene Information human ... MAOA(4128) rat ... Maoa(29253), Maob(25750)	Gene Information human ... MAOA(4128), MAOB(4129)	Gene Information human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340), SLC9A1(6548), SLC9A5(6553) mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278) rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768), Slc9a1(24782), Slc9a2(24783), Slc9a3(24784), Slc9a4(24785)	Gene Information human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)