If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
Scegli un formato
| A voi/SKU | Disponibilità | Prezzo |
|---|---|---|
50 g | Per conoscere la disponibilità, visualizza il carrello | CHF 281.00 |
250 g | Per conoscere la disponibilità, visualizza il carrello | CHF 1’070.00 |
1 kg | Per conoscere la disponibilità, visualizza il carrello | CHF 1’630.00 |
Informazioni su questo articolo
Quality Segment
assay
≥99% (titration)
form
powder
storage condition
dry at room temperature
impurities
≤1.0% water
color
white
pH
2.5-4 (25 °C, 97.6 g/L)
useful pH range
5.5-6.7
pKa
6.1
density
1.23 g/cm3 at 20—25 °C, 1.27 g/cm3 at 20—25 °C
application(s)
clinical research
diagnostic assay manufacturing
life science and biopharma (
)
metabolomics (
)
SMILES string
OS(=O)(=O)CCN1CCOCC1
InChI
1S/C6H13NO4S/c8-12(9,10)6-3-7-1-4-11-5-2-7/h1-6H2,(H,8,9,10)
InChI key
SXGZJKUKBWWHRA-UHFFFAOYSA-N
General description
Questo tampone multifunzionale trova applicazione diffusa nel preservare la stabilità dell′ambiente di soluzione di soluzioni da impiegare in terreni di coltura cellulare, in formulazioni tamponate contenenti proteine e in tamponi di corsa per elettroforesi. Le sue qualità risultano importanti anche nei processi di purificazione di anticorpi, peptidi, proteine, componenti ematici e fattori di crescita. Il tampone MES si fa preferire come prima scelta anche in elettrocromatografia capillare, assicurando bassa mobilità ionica. Nello specifico, viene impiegato come alternativa più sicura rispetto ad agenti potenzialmente tossici come il tampone cacodilato e i tamponi zwitterionici, tra cui il tampone citrato e il tampone malato. Il tampone MES si rivela assai utile per la regolazione fine del pH nei mezzi di crescita, per la stabilizzazione di soluzioni enzimatiche e come componente di un tampone di corsa PAGE in diversi contesti sperimentali.
Application
Features and Benefits
- Sottoposto a test che ne confermano i bassi livelli di contaminazione da metalli pesanti, garantendone l′idoneità ad un ampio ventaglio di applicazioni
- Tampone efficace nell′intervallo di pH 5,5-6,7 (25 °C), con una pKa di 6,1 (25 °C)
- Altamente idrosolubile
- Legame con ioni metallici minimo
- Meno tossico per le cellule rispetto ad altri tamponi, quali il Tris e il tampone fosfato
- Stabile in un ampio intervallo di pH
- Basso coefficiente di estinzione UV e reattività minima
Analysis Note
Other Notes
1 of 1
Questo articolo | |||
|---|---|---|---|
| assay ≥99% (titration) | assay ≥99.5% (titration) | assay ≥99.5% | assay ≥99.0% (T) |
| Quality Level 400 | Quality Level 400 | Quality Level 400 | Quality Level 200 |
| application(s) clinical research | application(s) agriculture | application(s) advanced drug delivery | application(s) agriculture |
| form powder | form crystalline powder | form crystalline powder | form powder or crystals |
| storage condition dry at room temperature | storage condition dry at room temperature | storage condition dry at room temperature | storage condition - |
| density 1.23 g/cm3 at 20—25 °C, 1.27 g/cm3 at 20—25 °C | density - | density - | density - |
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Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
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How can I determine the shelf life / expiration / retest date of this product?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the pH of a solution of Product M3671, MES - low moisture?
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The pH of a 0.5 M solution in water should be between 2.5 and 4.0.
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What is the solubility of Product M3671, MES - low moisture?
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We test the solubility of Prod. No. M3671 at 20 grams in 80 mL of water. A clear, colorless solution is obtained. This concentration is not necessarily the upper solubility limit of MES in water.
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Is Product M3671, MES - low moisture, autoclavable?
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Autoclaving is not recommended for any sulfonic acid buffer solution. Sterilization of a MES buffer solution can be accomplished by filtering it through a 0.2 micron filter.
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What does low moisture content mean in the description of Product M3671, MES - low moisture?
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The amount of water/moisture for MES (M3671) is tested by Karl Fisher and meets a specification of less than 1%. The other MES Hydrates offered have a specification of less than 9%.
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How does one prepare a buffer using Product M3671, MES - low moisture, free acid?
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A buffer using MES free acid can be prepared by titrating the free acid with sodium hydroxide to the desired pH. Alternatively, volumes of equimolar MES free acid and sodium MES can be mixed to attain the desired pH.
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