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M2398

Metaproterenol hemisulfate salt

Name: Metaproterenol hemisulfate salt
Brand: SIGMA

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Informazioni su questo articolo

Formula condensata:

C₁₁H₁₇NO₃ · 1/2H₂SO₄

Numero CAS:

5874-97-5

Peso molecolare:

260.30

NACRES:

NA.77

PubChem Substance ID:

24278539

UNSPSC Code:

12352107

EC Number:

227-539-6

MDL number:

MFCD00058303

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Proprietà

Quality Segment

100

originator

Boehringer Ingelheim

SMILES string

OS(O)(=O)=O.CC(C)NCC(O)c1cc(O)cc(O)c1.CC(C)NCC(O)c2cc(O)cc(O)c2

InChI

1S/2C11H17NO3.H2O4S/c2*1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8;1-5(2,3)4/h2*3-5,7,11-15H,6H2,1-2H3;(H2,1,2,3,4)

InChI key

MKFFGUZYVNDHIH-UHFFFAOYSA-N

Gene Information

human ... ADRB2(154)

Descrizione

Application

Metaproterenol hemisulfate salt has been used:

as a β2-adrenoceptor agonist to study its effects on adenylyl cyclase stimulation in red blood cell deformability
as an adrenergic agonist to study its effects on the stereoselective cell uptake by organic cation transporters in human embryonic kidney cell lines
as a bronchodilator to study its effects on the activation of G-protein coupled receptors (GPCR)

Biochem/physiol Actions

Metaproterenol is a β2-adrenoceptor agonist. It shows bronchodilator activity and shows therapeutic effects against bronchitis, asthma, and emphysema.

Features and Benefits

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Questo articolo	S5013	T2528	M149
Sigma-Aldrich M2398 Metaproterenol hemisulfate salt	Sigma-Aldrich S5013 Salbutamol hemisulfate salt	Sigma-Aldrich T2528 Terbutaline hemisulfate salt	Sigma-Aldrich M149 Methiothepin mesylate salt
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
originator Boehringer Ingelheim	originator GlaxoSmithKline	originator Novartis	originator -
Gene Information human ... ADRB2(154)	Gene Information human ... ADRB2(154)	Gene Information human ... ADRB1(153), ADRB2(154), ADRB3(155)	Gene Information human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR6(3362), HTR7(3363)