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M003

Sigma-Aldrich

R-(−)-Deprenyl hydrochloride

powder, ≥98% (HPLC)

Sinonimo/i:

(R)-(−)-N,α-Dimethyl-N-(2-propynyl)phenethylamine hydrochloride, R(−)-N-α-Dimethyl-N-2-propynyl-benzeneethanamine hydrochloride, Selegiline hydrochloride

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250 MG
CHF 138.00
1 G
CHF 283.00

CHF 138.00

Spedizione prevista il31 maggio 2025

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250 MG
CHF 138.00
1 G
CHF 283.00

About This Item

Formula empirica (notazione di Hill):
C13H17N · HCl
Numero CAS:
14611-52-0
Peso molecolare:
223.74
Numero MDL:
MFCD00069299
Codice UNSPSC:
12352200
ID PubChem:
24278577
NACRES:
NA.77

CHF 138.00

Spedizione prevista il31 maggio 2025

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Saggio

≥98% (HPLC)

Stato

powder

Attività ottica

[α]25/D −10.8°, c = 6.48 in H2O(lit.)

Colore

white

Punto di fusione

141-142  °C

Solubilità

H2O: >10 mg/mL

Ideatore

Sanofi Aventis

Stringa SMILE

Cl[H].C[C@H](Cc1ccccc1)N(C)CC#C

InChI

1S/C13H17N.ClH/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13;/h1,5-9,12H,10-11H2,2-3H3;1H/t12-;/m1./s1
IYETZZCWLLUHIJ-UTONKHPSSA-N

Informazioni sul gene

human ... MAOB(4129)

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Categorie correlate

Azioni biochim/fisiol

Selective MAO-B inhibitor; anti-Parkinsonian agent.

Caratteristiche e vantaggi

This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H336

Consigli di prudenza

P301 + P312 + P330

Classi di pericolo

Acute Tox. 4 Oral - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
0000398972
0000398973
0000398973
0000398972
0000393237

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Journal of agricultural and food chemistry, 72(30), 16777-16789 (2024-07-19)
Previous clinical studies indicate that monoamine oxidase-B (MAO-B) inhibition by blackcurrants must be predominantly attributed to bioactives other than anthocyanins. In this natural products discovery study, MAO-A/B inhibitory phytochemicals were isolated from blackcurrants, and a double-blind crossover study investigated the
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Mucosal epithelial cell integrity is an important component of innate immunity and it protects the host from an environment rich in microorganisms. Virulence factors from Gram-negative bacteria [e.g. lipopolysaccharide (LPS)] induce significant pro-inflammatory cytokine expression. Monoamine oxidase (MAO) inhibitors reduce
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Amyotrophic lateral sclerosis (ALS) is a devastating disorder in which motor neurons degenerate, the causes of which remain unclear. In particular, the basis for selective vulnerability of spinal motor neurons (sMNs) and resistance of ocular motor neurons to degeneration in
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