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I6284

Anti-Human IgE (ε-chain specific) antibody produced in goat

affinity isolated antibody, lyophilized powder

Sinonimo/i:

Anti Human Ige, Anti-Human IgE - Anti-Human IgE (ε-chain specific) antibody produced in goat, Anti-Human Ige

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Cambia visualizzazione
Taglio della confezioneSKUDisponibilitàPrezzo
1 mg
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CHF 428.00

Informazioni su questo articolo

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ODD
Citations:
9

CHF 428.00


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biological source

goat

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

Ouchterlony double diffusion: suitable

storage temp.

2-8°C

target post-translational modification

unmodified

General description

IgE is a class of immunoglobulins that is produced only in mammals. IgE is secreted by mast cells in response to allergens and is important in immunity against parasites. It also is the most important factor in the pathophysiology of anaphylaxis or type I hypersensitivity. The antibody preparation is specific for human IgE when tested against purified human IgA, IgG, IgM, Bence Jones κ, and Bence Jones λ proteins. Identity and purity of the antibody is established by immunoelectrophoresis.

Immunogen

Purified human IgE (myeloma)

Application

Anti-Human IgE (epsilon-chain specific) antibody may be used as a control in various immunoassays.

Physical form

Lyophilized from 0.01 M sodium phosphate, 0.015 M sodium chloride, pH 7.2.

Preparation Note

Reconstitute with 0.135 M sodium chloride to achieve a 1 mg/mL solution of antibody.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Questo articolo
I0884A3525I2136
technique(s)

Ouchterlony double diffusion: suitable

technique(s)

Ouchterlony double diffusion: suitable

technique(s)

direct ELISA: 1:7,000-1:21,000

technique(s)

indirect ELISA: 1:10,000

biological source

goat

biological source

goat

biological source

goat

biological source

goat

conjugate

unconjugated

conjugate

unconjugated

conjugate

alkaline phosphatase conjugate

conjugate

unconjugated

species reactivity

human

species reactivity

-

species reactivity

human

species reactivity

-

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

form

lyophilized powder

form

lyophilized powder

form

buffered aqueous glycerol solution

form

buffered aqueous solution


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Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Contenuto correlato

Instructions


Stephen J Galli et al.
Nature medicine, 18(5), 693-704 (2012-05-09)
Immunoglobulin E (IgE) antibodies and mast cells have been so convincingly linked to the pathophysiology of anaphylaxis and other acute allergic reactions that it can be difficult to think of them in other contexts. However, a large body of evidence
Bettina Wedi et al.
Allergy, 75(9), 2229-2242 (2020-02-01)
Mas-related G protein-coupled receptor X2 (MRGPRX2) is regarded as a mast cell-specific receptor mediating non-IgE-dependent activation. We aimed to investigate whether human basophils and eosinophils express functional MRGPRX2. Flow cytometry, immunocytochemistry, immunofluorescence, Western blot, and RT-PCR were performed in highly
Shiteng Duan et al.
The Journal of clinical investigation, 129(3), 1387-1401 (2019-01-16)
Allergen immunotherapy for patients with allergies begins with weekly escalating doses of allergen under medical supervision to monitor and treat IgE mast cell-mediated anaphylaxis. There is currently no treatment to safely desensitize mast cells to enable robust allergen immunotherapy with



Numero articolo commerciale globale

SKUGTIN
I6284-1MG04061826703373

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