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D7400

2′-Deoxyadenosine monohydrate

≥99%, synthetic (organic), powder

Sinonimo/i:

9-(2-Deoxy-β-D-ribofuranosyl)adenine, Adenine deoxyriboside

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Taglio della confezioneSKUDisponibilitàPrezzo
250 mg
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CHF 71.60
500 mg
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CHF 77.20
1 g
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CHF 112.00
5 g
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CHF 449.00
25 g
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CHF 858.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C10H13N5O3 · H2O
Numero CAS:
16373-93-6
Peso molecolare:
269.26
NACRES:
NA.51
PubChem Substance ID:
24894129
UNSPSC Code:
41106305
EC Number:
213-488-7
MDL number:
MFCD00005754
Beilstein/REAXYS Number:
91015
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
Storage temp.:
2-8°C

CHF 71.60

Per conoscere la disponibilità, visualizza il carrello
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Nome del prodotto

2′-Deoxyadenosine monohydrate, ≥99%

biological source

synthetic (organic)

Quality Level

200

assay

≥99%

form

powder

solubility

water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

[H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3

InChI

1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1

InChI key

OLXZPDWKRNYJJZ-RRKCRQDMSA-N

Application

2′-Deoxyadenosine monohydrate has been used:
  • as a component for nucleoside supplementation
  • as a standard for to estimate DNA global methylation rate in proliferating oil palm embryogenic suspensions
  • to reverse sterile alpha motif (SAM) and histidine-aspartate (HD) domain-containing protein (SAMHD1)
  • inhibition of human immunodeficiency virus (HIV-1) and hepatitis B virus (HBV)

Biochem/physiol Actions

2′-Deoxyadenosine (2′-dAdo), a deoxyribonucleoside, may be used by some cells as an energy source under energy stress conditions and to affect cAMP levels. 2′-dAdo is used in comparison studies of the functions of adenosine analogues on various biological processes.

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Questo articolo
D8668D5287D0901
2′-Deoxyadenosine monohydrate ≥99%

Sigma-Aldrich

D7400

2′-Deoxyadenosine monohydrate

2′-Deoxyadenosine monohydrate powder, BioReagent, suitable for cell culture

Sigma-Aldrich

D8668

2′-Deoxyadenosine monohydrate

2′-Deoxyinosine ≥98%

Sigma-Aldrich

D5287

2′-Deoxyinosine

2′-Deoxyguanosine monohydrate powder, BioReagent, suitable for cell culture, 99-100%

Sigma-Aldrich

D0901

2′-Deoxyguanosine monohydrate

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥99%

assay

≥99% (HPLC)

assay

≥98%

assay

99-100%

form

powder

form

powder

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

solubility

water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

H2O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

solubility

1 M NH4OH: 50 mg/mL

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Classe di stoccaggio

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

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Certificati d'analisi (COA)

Lot/Batch Number
0000535973
0000535973
0000504163
0000504150
0000504163

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M Nakamura et al.
The Journal of biological chemistry, 257(23), 13945-13950 (1982-12-10)
Regulation of glucose metabolism in glycolysis by round spermatids was studied. Assay of activities of 11 glycolytic enzymes in cell-free spermatid extracts showed that hexokinase, phosphofructokinase, and glyceraldehyde-3-phosphate dehydrogenase had the lowest activities. When the cells were incubated with glucose
O Magnus et al.
International journal of fertility, 38(2), 123-128 (1993-03-01)
To find differences in effect on sperm motility of agents that increase intracellular cAMP: manganese ion, methyl-isobutyl-xanthine (MIX), 2-deoxyadenosine, glucose, and Mn-MIX and Mn-glucose. Nine men with asthenozoospermia vs. fertile donors. Sperm was washed in Hepes-buffered saline, motility tested by
Michela Giannecchini et al.
The international journal of biochemistry & cell biology, 37(4), 797-808 (2005-02-08)
In this paper, we report that cells undergoing metabolic stress conditions may use the ribose moiety of nucleosides as energy source to slow down cellular damage. In fact, the phosphorolytic cleavage of the N-glycosidic bond of nucleosides generates, without energy
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Numero articolo commerciale globale

SKUGTIN
D7400-1G04061826738429
D7400-250MG04061833048030
D7400-500MG04061833588475
D7400-25G04061833588468
D7400-5G04061833588482

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