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C127

Sigma-Aldrich

CNQX

≥98% (HPLC), solid

Sinonimo/i:

6-Cyano-7-nitroquinoxaline-2,3-dione, FG-9065

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About This Item

Formula empirica (notazione di Hill):
C9H4N4O4
Numero CAS:
115066-14-3
Peso molecolare:
232.15
Numero MDL:
MFCD00069232
Codice UNSPSC:
12352200
ID PubChem:
24892392
NACRES:
NA.77

Livello qualitativo

100

Saggio

≥98% (HPLC)

Forma fisica

solid

Condizioni di stoccaggio

protect from light

Colore

yellow

Solubilità

DMSO: >10 mg/mL
H2O: insoluble

Stringa SMILE

[O-][N+](=O)c1cc2NC(=O)C(=O)Nc2cc1C#N

InChI

1S/C9H4N4O4/c10-3-4-1-5-6(2-7(4)13(16)17)12-9(15)8(14)11-5/h1-2H,(H,11,14)(H,12,15)
RPXVIAFEQBNEAX-UHFFFAOYSA-N

Informazioni sul gene

rat ... Gria1(50592) , Grik1(29559) , Grik2(54257) , Grik4(24406) , Grin2a(24409)

Applicazioni

CNQX has been used:
  • as an α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate blocker to study its effects on cytoneme formation in pluripotent embryonic stem cells (pESCs)
  • glutamate blocker to reduce the synaptic input during current-clamp recordings in central antennal lobe neurons
  • as a non-N-methyl-D-aspartate (NMDA) receptor blocker to study its effects on the heart rate in rats

Azioni biochim/fisiol

Potent, competitive AMPA/kainate glutamate receptor antagonist.

Altre note

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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