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D0540

Sigma-Aldrich

DNQX

≥98% (TLC)

Sinonimo/i:

6,7-Dinitroquinoxaline-2,3(1H,4H)-dione

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About This Item

Formula empirica (notazione di Hill):
C8H4N4O6
Numero CAS:
2379-57-9
Peso molecolare:
252.14
Numero MDL:
MFCD00069257
Codice UNSPSC:
51111800
ID PubChem:
24277973
NACRES:
NA.77

Livello qualitativo

200

Saggio

≥98% (TLC)

Forma fisica

powder

Stringa SMILE

[O-][N+](=O)c1cc2NC(=O)C(=O)Nc2cc1[N+]([O-])=O

InChI

1S/C8H4N4O6/c13-7-8(14)10-4-2-6(12(17)18)5(11(15)16)1-3(4)9-7/h1-2H,(H,9,13)(H,10,14)
RWVIMCIPOAXUDG-UHFFFAOYSA-N

Informazioni sul gene

human ... GRIA1(2890) , GRIA2(2891) , GRIK1(2897) , GRIK2(2898) , GRIK3(2899) , GRIK4(2900) , GRIK5(2901)
mouse ... Gria1(14799)
rat ... Gria1(50592) , Grik1(29559) , Grik4(24406) , Grin2a(24409)

Applicazioni

DNQX has been used to block N-Methyl-D-aspartic acid (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in various experiments.

Azioni biochim/fisiol

DNQX is a quinoxaline derivative.
A competitive kainate, quisqualate (non-NMDA) glutamate receptor antagonist.

Caratteristiche e vantaggi

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Certificati d'analisi (COA)

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