I accidentally bought this thinking it was MTT salt to use in a cell proliferation assay but it is MTT Formazan, the water insoluble end product! Therefore, it is useless for the assay. I suppose you could use it as a control to optimize your buffer for solubilizing the insoluble Formazan. The description for this product is misleading and should clarify that this is not what you need for an MTT assay, and refer the customer to MTT salt. That said, this is a nice purple crystalline powder and insoluble in water consistent with MTT Formazan, if that is what you actually want.
88417
MTT Formazan
MTT Formazan
MTT reduction end product, powder
Sinonimo/i:
Thiazolyl blue formazan
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250 MG
CHF 46.90
1 G
CHF 158.00
CHF 46.90
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Cambia visualizzazione
250 MG
CHF 46.90
1 G
CHF 158.00
About This Item
Formula empirica (notazione di Hill):
C18H17N5S
Numero CAS:
Peso molecolare:
335.43
Numero MDL:
Codice UNSPSC:
12352204
ID PubChem:
NACRES:
NA.83
CHF 46.90
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Prodotti consigliati
Nome del prodotto
MTT Formazan, MTT reduction end product
Stato
powder
Solubilità
chloroform: 10 mg/mL, clear, dark violet
Stringa SMILE
Cc1nc(\N=N\C(=N\Nc2ccccc2)c3ccccc3)sc1C
InChI
1S/C18H17N5S/c1-13-14(2)24-18(19-13)23-22-17(15-9-5-3-6-10-15)21-20-16-11-7-4-8-12-16/h3-12,20H,1-2H3/b21-17+,23-22+
GIFKVQOPAJDJLO-SZVLODPRSA-N
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Azioni biochim/fisiol
MTT assay is a colorimetric reaction, generally used to examine cell viability. It involves the enzymatic reduction of a yellow-colored, water-soluble, 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) to purple-colored, water-insoluble, MTT-formazan. This reaction is catalyzed by mitochondrial dehydrogenase and only occurs in viable cells.[4][5] Thus, the amount of blue formazan is proportional to the number of viable cells. The absorbance of the formazan solution is analyzed spectrophotometrically at 570 nm.[6]
Altre note
Reviews: Tetrazolium salts and formazans[7]
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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