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07039

(R)-(+)-α-Lipoic acid

≥98.0% (HPLC)

Sinonimo/i:

(R)-(+)-1,2-Dithiolane-3-pentanoic acid, (R)-6,8-Dithiooctanoic acid, (R)-6,8-Thioctic acid

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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C8H14O2S2
Numero CAS:
Peso molecolare:
206.33
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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Quality Segment

assay

≥98.0% (HPLC)

optical purity

enantiomeric excess: ≥98.0% (HPLC)

mp

48-52 °C (lit.)

storage temp.

−20°C

InChI

1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1

InChI key

AGBQKNBQESQNJD-SSDOTTSWSA-N

Biochem/physiol Actions

(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes.[1] It is a biological antioxidant with prooxidant activities[2][3], its therapeutic potential is widely investigated[4][5][6], e.g. in the treatment for Alzheimer′s disease.[7]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Analysis Note

identity confirmed by LC-MS

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Questo articolo
0856104471Y0000546
Thioctic acid European Pharmacopoeia (EP) Reference Standard

Y0000546

Thioctic acid

Quality Level

100

Quality Level

100, 200

Quality Level

100

Quality Level

-

assay

≥98.0% (HPLC)

assay

≥97% (HPLC)

assay

≥98.0% (HPLC)

assay

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

optical purity

enantiomeric excess: ≥98.0% (HPLC)

optical purity

enantiomeric excess: ≥98.0% (HPLC)

optical purity

-

optical purity

-

mp

48-52 °C (lit.)

mp

-

mp

48-52 °C (lit.)

mp

-


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Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3



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Questions

  1. What is REF 07039 Lipoic Acid soluble in?

    1 answer
    1. The solubility of this product has not been determined. However, the cell culture tested (±)-α-Lipoic acid, product T1395, is soluble at 50 mg/mL in ethanol. Similar solubility is expected for this item. In addition, various sources indicate this compound is also soluble in DMSO, acetonitrile, and chloroform. This information has not been validated.

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