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Merck
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Documenti

09415

Sigma-Aldrich

Sodium 4-aminosalicylate dihydrate

≥97.0% (T)

Sinonimo/i:

4-Amino-2-hydroxybenzoic acid sodium salt, 4-Amino-salicylic acid sodium salt

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About This Item

Formula empirica (notazione di Hill):
C7H6NNaO3 · 2H2O
Numero CAS:
6018-19-5
Peso molecolare:
211.15
Numero CE:
205-091-2
Numero MDL:
MFCD00151044
Codice UNSPSC:
41116107
ID PubChem:
329748763
NACRES:
NA.22

Livello qualitativo

200

Saggio

≥97.0% (T)

Forma fisica

powder

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

tecniche

ligand binding assay: suitable

Colore

white to faintly beige

applicazioni

peptide synthesis

Stringa SMILE

O.O.[Na+].Nc1ccc(c(O)c1)C([O-])=O

InChI

1S/C7H7NO3.Na.2H2O/c8-4-1-2-5(7(10)11)6(9)3-4;;;/h1-3,9H,8H2,(H,10,11);;2*1H2/q;+1;;/p-1
GMUQJDAYXZXBOT-UHFFFAOYSA-M

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Categorie correlate

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
0001257115
1257115
1140896
1257115V
453791/1

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Sumit Chakraborty et al.
Science (New York, N.Y.), 339(6115), 88-91 (2012-11-03)
Folate biosynthesis is an established anti-infective target, and the antifolate para-aminosalicylic acid (PAS) was one of the first anti-infectives introduced into clinical practice on the basis of target-based drug discovery. Fifty years later, PAS continues to be used to treat
Cezary Chojnacki et al.
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 31(182), 92-96 (2011-09-23)
In order to maintain ulcerative colitis (UC) in remission, chronic use of aminosalicylates is recommended. All patients have a fear of the recurrence of symptoms, which makes their mental state and quality of life worse. Because of this a number
Amanda S Fivian-Hughes et al.
Microbiology (Reading, England), 158(Pt 2), 308-318 (2011-10-29)
Thymidylate synthase (TS) enzymes catalyse the biosynthesis of deoxythymidine monophosphate (dTMP or thymidylate), and so are important for DNA replication and repair. Two different types of TS proteins have been described (ThyA and ThyX), which have different enzymic mechanisms and
A C Liwa et al.
Journal of tropical pediatrics, 59(2), 90-94 (2012-11-24)
There are no paediatric data regarding slow-release para-aminosalicylic acid (PAS). We studied PAS plasma concentrations in 10 children receiving a single 150 mg/kg dose daily or 75 mg/kg twice daily and 12 adults receiving 4 g twice daily. Blood specimens
S M Vesenbeckh et al.
Infection, 40(2), 199-202 (2011-08-13)
para-Aminosalicylic acid (PAS) is commonly used in the treatment of drug-resistant tuberculosis, including multidrug-resistant tuberculosis. Since its first use in the 1940s, hypersensitivity reactions frequently limit its use in clinical practice. Cases of successful desensitization against PAS using orally administered
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