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AB2233

Sigma-Aldrich

Anti-Galanin Antibody

serum, from rabbit

Sinonimo/i:

galanin prepropeptide, galanin-message-associated peptide, galanin-related peptide

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100 μL
CHF 424.00

CHF 424.00


Spedizione prevista il26 maggio 2025


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100 μL
CHF 424.00

About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CHF 424.00


Spedizione prevista il26 maggio 2025


Richiedi un ordine bulk

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

serum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

rat

Reattività contro le specie (prevista in base all’omologia)

mouse, boar, human

tecniche

immunohistochemistry: suitable (paraffin)

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... GAL(51083)

Descrizione generale

Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR’s) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it’s receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer′s disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.

Specificità

Cat. # AB2233 recognizes Galanin
Reactivity with other species has not been determined.

Immunogeno

Synthetic Linear Peptide

Applicazioni

Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Qualità

Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.

Descrizione del bersaglio

13.3 kDa

Stato fisico

Serum with 0.05% NaN3

Stoccaggio e stabilità

Maintain at -20°C for up to 1 year from date of receipt.

Risultati analitici

Control
Rat Cerebellum Tissue

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1


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Anatomia, histologia, embryologia, 47(6), 517-526 (2018-08-15)
The gastrointestinal (GI) tract is innervated by nerve processes derived from the intramural enteric neurons and neurons localized outside the digestive tract. This study analysed the neurochemical characterization of nerves in the wall of the porcine oesophagus using single immunofluorescence
Yutaro Komuro et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(42), 8725-8741 (2021-09-01)
Galanin, one of the most inducible neuropeptides, is widely present in developing brains, and its expression is altered by pathologic events (e.g., epilepsy, ischemia, and axotomy). The roles of galanin in brain development under both normal and pathologic conditions have
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