V900286
2-Aminopyrimidine
Vetec™, reagent grade, 97%
Sinonimo/i:
2-Pyrimidinamine
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Informazioni su questo articolo
Formula empirica (notazione di Hill):
C4H5N3
Numero CAS:
Peso molecolare:
95.10
EC Number:
203-648-4
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
107014
MDL number:
Assay:
97%
Prezzi e disponibilità al momento non sono disponibili
Servizio Tecnico
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Permettici di aiutartigrade
reagent grade
product line
Vetec™
assay
97%
mp
122-126 °C (lit.)
SMILES string
Nc1ncccn1
InChI
1S/C4H5N3/c5-4-6-2-1-3-7-4/h1-3H,(H2,5,6,7)
InChI key
LJXQPZWIHJMPQQ-UHFFFAOYSA-N
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Kamaljit Singh et al.
European journal of medicinal chemistry, 52, 82-97 (2012-03-31)
2-Aminopyrimidine based 4-aminoquinolines were synthesized using an efficacious protocol. Some of the compounds showed in vitro anti-plasmodial activity against drug-sensitive CQ(S) (3D7) and drug-resistant CQ(R) (K1) strains of Plasmodium falciparum in the nM range. In particular, 5-isopropyloxycarbonyl-6-methyl-4-(2-nitrophenyl)-2-[(7-chloroquinolin-4-ylamino)butylamino] pyrimidine depicted the lowest
Robert J Altenbach et al.
Journal of medicinal chemistry, 51(20), 6571-6580 (2008-09-25)
A series of 2-aminopyrimidines was synthesized as ligands of the histamine H4 receptor (H4R). Working in part from a pyrimidine hit that was identified in an HTS campaign, SAR studies were carried out to optimize the potency, which led to
D S Ermolat'ev et al.
Molecular diversity, 15(2), 491-496 (2010-08-27)
An efficient microwave-assisted one-pot two-step protocol was developed for the construction of disubstituted 2-amino-1H-imidazoles. This process involves the sequential formation of 2,3-dihydro-2-hydroxyimidazo[1,2-a]pyrimidinium salts from readily available 2-aminopyrimidines and α-bromoketones, followed by cleavage of the pyrimidine ring with hydrazine.