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1708762

USP

Valsartan

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

N-(1-Oxopentyl)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine

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About This Item

Formula empirica (notazione di Hill):
C24H29N5O3
Numero CAS:
137862-53-4
Peso molecolare:
435.52
Numero MDL:
MFCD00865840
Codice UNSPSC:
41116107
ID PubChem:
329751479
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

valsartan

Produttore/marchio commerciale

USP

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

CCCCC(=O)N(Cc1ccc(cc1)-c2ccccc2-c3nnn[nH]3)[C@@H](C(C)C)C(O)=O

InChI

1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
ACWBQPMHZXGDFX-QFIPXVFZSA-N

Informazioni sul gene

human ... AGTR1(185)

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Categorie correlate

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Valsartan USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Valsartan Tablets
  • Amlodipine and Valsartan Tablets
  • Valsartan and Hydrochlorothiazide Tablets
  • Amlodipine, Valsartan, and Hydrochlorothiazide Tablets

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Warning

Indicazioni di pericolo

H336,H361d

Consigli di prudenza

P201 - P308 + P313

Classi di pericolo

Repr. 2 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Valsartan Related Compound B Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1876

Valsartan Related Compound B

Amlodipine besylate United States Pharmacopeia (USP) Reference Standard

USP

1029501

Amlodipine besylate

LBQ657 ≥97% (HPLC)

Sigma-Aldrich

SML2064

LBQ657

Valsartan for peak identification European Pharmacopoeia (EP) Reference Standard

Y0001131

Valsartan for peak identification

USP

USP

1708810

Valsartan Related Compound E

USP

USP

1606015

Rosuvastatin Calcium

Valsartan Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1877

Valsartan Related Compound C

Rosuvastatin Calcium Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1928

Rosuvastatin Calcium

USP

USP

1029512

Amlodipine Related Compound A

Irbesartan ≥98% (HPLC), powder

Sigma-Aldrich

I2286

Irbesartan

Zhenfeng Zheng et al.
Journal of clinical hypertension (Greenwich, Conn.), 12(6), 414-421 (2010-07-02)
This was a systematic assessment of the efficacy and safety of telmisartan and valsartan for the management of blood pressure (BP) in patients with essential hypertension. The authors reviewed randomized controlled trials (RCTs) and quasi-RCTs comparing telmisartan and valsartan for
Henry R Black et al.
Drugs, 69(17), 2393-2414 (2009-11-17)
Valsartan is a nonpeptide angiotensin receptor antagonist that selectively blocks the binding of angiotensin II to the angiotensin II type 1 receptor. The efficacy, tolerability and safety of valsartan have been demonstrated in large-scale studies in hypertension, heart failure (HF)
Adriaan A Voors et al.
Expert opinion on investigational drugs, 22(8), 1041-1047 (2013-05-15)
Heart failure remains a syndrome with a very high mortality rate and a poor quality of life. For patients with heart failure and a preserved ejection fraction (HFpEF), no drugs have shown to improve mortality and morbidity, and therefore novel
Erdal Tan Ishizuka et al.
Investigative ophthalmology & visual science, 56(1), 74-80 (2014-12-17)
Extranodal marginal zone B-cell lymphoma (EMZL) is the most common subtype of conjunctival lymphoma, though its molecular mechanisms of pathogenesis are largely unknown. We attempted to explore the association of the renin-angiotensin system (RAS) and (pro)renin receptor ([P]RR) in the
Roberto Fogari et al.
Expert opinion on drug safety, 10(2), 295-303 (2010-12-15)
Angiotensin receptor blockers (ARBs) as a class are generally considered safe and better tolerated than other antihypertensive drugs. The purpose of this report is to review the main data on the safety and tolerability of the second generation ARB valsartan
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