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USP

Nicotine bitartrate dihydrate

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

(−)-Nicotine hydrogen tartrate salt dihydrate

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Taglio della confezioneSKUDisponibilitàPrezzo
400 mg
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CHF 412.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C10H14N2 · 2C4H6O6 · 2H2O
Numero CAS:
Peso molecolare:
498.44
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

CHF 412.00


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grade

pharmaceutical primary standard

agency

USP

API family

nicotine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Clc1cc2c(cc1)O\C(=C3\C=C(C=CC\3=O)NC(=O)C(C)C)\N2

InChI

1S/C17H15ClN2O3/c1-9(2)16(22)19-11-4-5-14(21)12(8-11)17-20-13-7-10(18)3-6-15(13)23-17/h3-9,20H,1-2H3,(H,19,22)/b17-12-

InChI key

YGMGVHYZWYRTJJ-ATVHPVEESA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Nicotine bitartrate dihydrate USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, system suitability, sensitivity, and standard stock solution for assay, identification, performance test, and impurity analysis according to the given below monographs of United States Pharmacopeia (USP):
  • Nicotine
  • Nicotine Polacrilex
  • Nicotine Transdermal System

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Questo articolo
Y0001425PHR2532N0590200
Nicotine ditartrate European Pharmacopoeia (EP) Reference Standard

N0590200

Nicotine ditartrate

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

EDQM

format

neat

format

neat

format

-

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

-

API family

nicotine

API family

nicotine

API family

nicotine

API family

nicotine


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - STOT RE 1

Classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable



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Nicotine Transdermal System
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(2), 3153-3153 (2021)
Cheng Xiao et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(9), 3734-3746 (2015-03-06)
The glutamatergic subthalamic nucleus (STN) exerts control over motor output through nuclei of the basal ganglia. High-frequency electrical stimuli in the STN effectively alleviate motor symptoms in movement disorders, and cholinergic stimulation boosts this effect. To gain knowledge about the
Brandon J Henderson et al.
The Journal of general physiology, 143(1), 51-66 (2014-01-01)
Chronic exposure to nicotine up-regulates high sensitivity nicotinic acetylcholine receptors (nAChRs) in the brain. This up-regulation partially underlies addiction and may also contribute to protection against Parkinson's disease. nAChRs containing the α6 subunit (α6* nAChRs) are expressed in neurons in



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SKUGTIN
1463304-400MG04061838346094

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