1143008

Cocaine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: Ecgonine methyl ester benzoate hydrochloride
• Formula empirica (notazione di Hill): C₁₇H₂₁NO₄ · HCl
• Numero CAS: 53-21-4
• Peso molecolare: 339.81
• Numero MDL: MFCD00058119
• Codice UNSPSC: 41116107
• ID PubChem: 329749446
• NACRES: NA.24

Proprietà

• Grado: pharmaceutical primary standard
• Famiglia di API: cocaine
• Produttore/marchio commerciale: USP
• Controllo stupefacenti: USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Stringa SMILE: Cl.COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3
• InChI: 1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1; PIQVDUKEQYOJNR-VZXSFKIWSA-N

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Cocaine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Cocaine
• Cocaine Hydrochloride
• Cocaine Hydrochloride Tablets for Topical Solution

Azioni biochim/fisiol

Inhibits the dopamine, norepinephrine, and serotonin transporters with K_is of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

Risultati analitici

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H300 + H330,H336,H361d
• Consigli di prudenza: P202 - P260 - P264 - P271 - P280 - P304 + P340 + P310
• Classi di pericolo: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3
• Organi bersaglio: Central nervous system
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable