1000818

Abiraterone acetate

United States Pharmacopeia (USP) Reference Standard

• Sinonimo/i: 17-(Pyridin-3-yl)androsta-5,16-dien-3β-yl acetate
• Formula empirica (notazione di Hill): C₂₆H₃₃NO₂
• Numero CAS: 154229-18-2
• Peso molecolare: 391.55
• NACRES: NA.24
• PubChem Substance ID: 329748877
• UNSPSC Code: 41116107
• MDL number: MFCD00934213

Proprietà

• grade: pharmaceutical primary standard
• agency: USP
• API family: abiraterone
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: C[C@]12C(C[C@@H](OC(C)=O)CC2)=CC[C@]3([H])[C@]1([H])CC[C@@]4(C)[C@@]3([H])CC=C4C5=CC=CN=C5
• InChI: 1S/C26H33NO2/c1-17(28)29-20-10-12-25(2)19(15-20)6-7-21-23-9-8-22(18-5-4-14-27-16-18)26(23,3)13-11-24(21)25/h4-6,8,14,16,20-21,23-24H,7,9-13,15H2,1-3H3/t20-,21-,23-,24-,25-,26+/m0/s1
• InChI key: UVIQSJCZCSLXRZ-UBUQANBQSA-N
• Gene Information: human ... CYP17A1(1586)

Descrizione

General description

Abiraterone acetate is a pro-drug of abiraterone[1] and a potent inhibitor of the enzyme CYP17, required for androgen biosynthesis in the adrenal glands, testes and prostate tissue.

Application

Abiraterone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Abiraterone Acetate Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Informazioni sulla sicurezza

• pictograms: GHS08,GHS09
• signalword: Danger
• hcodes: H360F,H373,H410
• pcodes: P202 - P260 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Chronic 1 - Repr. 1B - STOT RE 2
• target_organs: Endocrine system
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable