SML0765
SR1555
≥98% (HPLC)
Sinonimo/i:
1,1,1,3,3,3-Hexafluoro-2-(4′-((1-(acetyl) piperazine) methyl)-[1,1′-biphenyl]-4-yl)propan-2-ol
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Informazioni su questo articolo
Formula empirica (notazione di Hill):
C22H22F6N2O2
Numero CAS:
Peso molecolare:
460.41
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 15 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
SR1555 is a selective RORγ inverse agonist that inhibits the development and function of TH17 cells, a subset of T cells that have been implicated in the pathology of several autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. SR1555 also increases the frequency of T regulatory cells, an effect not seen with previously described RORγ ligands.
SR1555 is a selective RORγ inverse agonist.
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Questo articolo | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level - | Quality Level 100 |
| storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| solubility DMSO: 15 mg/mL, clear | solubility DMSO: 5 mg/mL, clear (warmed) | solubility DMSO: 2 mg/mL, clear | solubility DMSO: >5 mg/mL |
| color white to beige | color white to beige | color white to faint brown | color white to beige |
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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