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Documenti

P9879

Sigma-Aldrich

Procaine hydrochloride

≥97% (HPLC), powder, Na⁺ channel blocker

Sinonimo/i:

4-Aminobenzoic acid 2-diethylaminoethyl ester, p-Aminobenzoic acid diethylaminoethyl ester hydrochloride, Novocaine hydrochloride

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About This Item

Formula condensata:
H2NC6H4CO2CH2CH2N(C2H5)2·HCl
Numero CAS:
51-05-8
Peso molecolare:
272.77
Beilstein:
3917802
Numero CE:
200-077-2
Numero MDL:
MFCD00013000
Codice UNSPSC:
12352200
ID PubChem:
24278665
NACRES:
NA.77

product name

Procaine hydrochloride, ≥97%

Saggio

≥97%

Forma fisica

powder

Punto di fusione

155-156 °C (lit.)

Ideatore

Celgene

Stringa SMILE

Cl.CCN(CC)CCOC(=O)c1ccc(N)cc1

InChI

1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H
HCBIBCJNVBAKAB-UHFFFAOYSA-N

Informazioni sul gene

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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Applicazioni

Procaine hydrochloride has been used as a component of Krebs Henseleit buffer for incubating the left ventricular cardiac tissue in its resting length. It has also been used as an inducer in M9 media for induction assay.

Azioni biochim/fisiol

Procaine is a Na+ channel blocker, commonly used as an anesthetic agent and is considered safer than cocaine. It is also useful as a painkiller to treat pain, associated with joints and tendons.

Caratteristiche e vantaggi

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Celgene. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H301,H317

Classi di pericolo

Acute Tox. 3 Oral - Skin Sens. 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificati d'analisi (COA)

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Ophthalmic Anaesthesia, 5-5 (2002)
Equine Anesthesia E-Book: Monitoring and Emergency Therapy, 215-215 (2002)
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Journal of neurophysiology, 81(5), 2386-2397 (1999-05-13)
of quantal end-plate currents of mouse muscle by physostigmine and procaine. Quantal endplate currents (qEPCs) were recorded from hemidiaphragms of mice by means of a macro-patch-clamp electrode. Excitation was blocked with tetrodotoxin, and quantal release was elicited by depolarizing pulses
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