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M5170

Sigma-Aldrich

IgM, Lambda from murine myeloma

clone MOPC 104E, purified immunoglobulin, buffered aqueous solution

Sinonimo/i:

Mouse IgM-λ

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

mouse

Coniugato

unconjugated

Forma dell’anticorpo

purified immunoglobulin

Clone

MOPC 104E, monoclonal

Forma fisica

buffered aqueous solution

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

modifica post-traduzionali bersaglio

unmodified

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Descrizione generale

IgM antibodies are present as pentamers in the serum and are produced in response to antigens
IgM, λ from murine myeloma is produced by MOPC 104E tumor line introduced subcutaneously in BALB/c mice. It specifically recognizes mouse IgM, λ. Identity and purity of the immunoglobulin is established by immunoelectrophoresis.

Specificità

Antigen Specificity: α(1→3) glucose

Applicazioni

IgM, λ from murine myeloma was used as standard in ELISA and as isotype control in immunohistochemistry applications.

Azioni biochim/fisiol

IgM antibodies are produced initially during B-cell development. IgM participates in opsonization and compliment fixation. Defect in IgM production is observed in X-linked agammaglobulinemia.

Stato fisico

Solution in 0.05 M Tris, 0.5 M sodium chloride, pH 8.0, containing 0.02% sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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The immunodominant region of the Plasmodium falciparum circumsporozoite protein is comprised mainly of a series of tetrapeptide repeats that can, depending on the starting cadence chosen, be described as (NANP)n, (ANPN)n, (NPNA)n or (PNAN)n in one-letter amino acid code. Data
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Frontiers in microbiology, 8, 2706-2706 (2018-02-07)
Aspergillus fumigatus is a filamentous fungus that can cause a life-threatening invasive pulmonary aspergillosis (IPA) in immunocompromised individuals. We previously characterized an exo-sialidase from A. fumigatus that prefers the sialic acid substrate, 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (Kdn); hence it is a Kdnase.
Establishment of fetal bovine intestinal epithelial cell cultures susceptible to bovine rotavirus infection
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Mucosal epithelial cells are infected by a wide variety of pathogens and determining their response to infection is critical for understanding disease pathogenesis. A protocol was developed for culturing primary epithelial cells from fetal bovine intestine and the cultured cells
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Influenza viruses are a group of respiratory pathogens that have evolved into four different types: A, B, C, and D. A common feature is that all four types are capable of replicating and transmitting among pigs. Here, we describe the

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