M109
2-Methylserotonin maleate salt
≥98% (HPLC)
Sinonimo/i:
2-Methyl-5-hydroxytryptamine maleate salt, 3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol maleate salt
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Informazioni su questo articolo
Formula empirica (notazione di Hill):
C11H14N2O · C4H4O4
Numero CAS:
Peso molecolare:
306.31
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Servizio Tecnico
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Permettici di aiutartiassay
≥98% (HPLC)
form
solid
color
tan
solubility
H2O: 4.5 mg/mL
storage temp.
−20°C
SMILES string
OC(=O)\C=C/C(O)=O.Cc1[nH]c2ccc(O)cc2c1CCN
Gene Information
human ... HTR3A(3359), HTR3B(9177)
Biochem/physiol Actions
5-HT3 serotonin receptor agonist.
Classe di stoccaggio
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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D M Gillies et al.
European journal of pharmacology, 303(1-2), 1-12 (1996-05-06)
5-Hydroxytryptamine (5-HT) is involved in the modulation of dopaminergic activity in the mesolimbic system, but its sites of action and the receptors involved are not well understood. Locomotor activity responses in rats were monitored in Animex automated activity boxes following
T Endo et al.
Research communications in molecular pathology and pharmacology, 104(2), 145-155 (2000-01-14)
The object of this study was to evaluate the involvement of 5-HT3 receptors in the regulation of 5-HT release from the small intestine using ferrets, an animal model of emesis. 2-Methyl-5-HT, a 5-HT3 receptor agonist, produced a concentration-dependent increase of
A M Ismaiel et al.
Journal of medicinal chemistry, 33(2), 755-758 (1990-02-01)
alpha-Methyl-5-hydroxytryptamine (alpha-Me-5-HT; 2) and 2-methyl-5-hydroxytryptamine (2-Me-5-HT; 3) are considered to be 5-HT2-selective and 5-HT3-selective agents, respectively. These agents were synthesized and examined at serotonin (5-HT) binding sites because there is relatively little documentation as to their selectivity and because they