M0267

(±)-Methadone hydrochloride

powder, ≥98%

• Sinonimo/i: 6-Dimethylamino-4,4-diphenylheptan-3-one hydrochloride
• Formula empirica (notazione di Hill): C₂₁H₂₇NO · HCl
• Numero CAS: 1095-90-5
• Peso molecolare: 345.91
• NACRES: NA.77
• PubChem Substance ID: 24896546
• UNSPSC Code: 12352200
• EC Number: 214-140-7
• MDL number: MFCD00058014
• Assay: ≥98%
• Form: powder

Proprietà

• Quality Segment: 200
• assay: ≥98%
• form: powder
• drug control: USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal), kontrollierte Droge in Deutschland
• color: white to off-white
• solubility: H₂O: 50 mg/mL, clear, colorless to yellow
• originator: Novartis
• SMILES string: Cl.CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c2ccccc2
• InChI: 1S/C21H27NO.ClH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H
• InChI key: FJQXCDYVZAHXNS-UHFFFAOYSA-N
• Gene Information: human ... OPRM1(4988)

Descrizione

Biochem/physiol Actions

μ opioid receptor agonist that desensitizes both the μ opioid receptor and the δ opioid receptor on chronic exposure; narcotic analgesic, characterized by a gradual onset of action and prolonged, milder withdrawal; may also block L-type calcium channels independently of its effects on opioid receptors.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

Informazioni sulla sicurezza

• pictograms: GHS06
• signalword: Danger
• hcodes: H300,H336
• pcodes: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P312 - P403 + P233
• Hazard Classifications: Acute Tox. 2 Oral - STOT SE 3
• target_organs: Central nervous system
• Classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges