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F0267

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys

≥97% (HPLC)

Autenticati per visualizzare i prezzi organizzativi e contrattuali.

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C43H65N7O9
Numero CAS:
71901-21-8
Peso molecolare:
824.02
UNSPSC Code:
12352200
PubChem Substance ID:
24894717
MDL number:
MFCD00076348

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CCCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCC)C(=O)NC(Cc2ccc(O)cc2)C(=O)NC(CCCCN)C(O)=O

Biochem/physiol Actions

Potent chemoattractant for human neutrophils.
Radioiodinated molecule has full biological activity.

Classe di stoccaggio

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
127H0346
124K0817
060K1747
044H0109
101K2185

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V Radhika et al.
American journal of hematology, 52(3), 155-164 (1996-07-01)
Binding of chemoattractant to polymorphonuclear leukocytes (PMNL) triggers a series of events like polymerization of actin and tubulin, orientation of cells, chemotaxis, increase in fluid pinocytosis and phagocytosis, and stimulation of microbicidal pathways which includes lysosomal degranulation and generation of
L A Sklar et al.
Proceedings of the National Academy of Sciences of the United States of America, 78(12), 7540-7544 (1981-12-01)
Antifluorescein antibody molecules were used to interrupt the stimulation of neutrophils by a fluoresceinated chemotactic peptide. From the results we construct a semiquantitative relationship among ligand-receptor interaction, the time course of cell triggering and response, and aspects of cellular adaptation.
A Volz
Journal of cell science, 106 ( Pt 2), 493-501 (1993-10-01)
The study analyses the distribution and quantitative expression of surface CD18 of neutrophils exposed to distinct stimuli that produce different types of continuous shape changes, including types that are associated with locomotion and others that are not. The chemotactic peptide
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