good service and product quality, arrived on time and the correct chemical.
E2011
cis-5,8,11,14,17-Eicosapentaenoic acid
from fish oil, ≥99% (GC), liquid, 5-Lipoxygenase inhibitor
cis-5,8,11,14,17-Eicosapentaenoic acid
1 of 1 reviewers received a sample product or took part in a promotion
Sinonimo/i:
EPA, Timnodonic acid
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Cambia visualizzazione
| Taglio della confezione | SKU | Disponibilità | Prezzo |
|---|---|---|---|
| 10 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 428.00 | |
| 25 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 517.00 | |
| 50 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 716.00 | |
| 100 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 1’440.00 |
Informazioni su questo articolo
Formula condensata:
CH3(CH2CH=CH)5(CH2)3CO2H
Numero CAS:
Peso molecolare:
302.45
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
Beilstein/REAXYS Number:
1714433
Servizio Tecnico
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Permettici di aiutartiNome del prodotto
cis-5,8,11,14,17-Eicosapentaenoic acid, ≥99%
biological source
fish oil
Quality Level
assay
≥99%
form
liquid
refractive index
n20/D 1.4977 (lit.)
mp
−54-−53 °C (lit.)
solubility
methanol: 50 mg/mL, clear, colorless
density
0.943 g/mL at 25 °C (lit.)
storage temp.
−20°C
SMILES string
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
InChI
1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-
InChI key
JAZBEHYOTPTENJ-JLNKQSITSA-N
Gene Information
human ... ALOX5(240)
mouse ... ALOX5(11689), Pparg(19016)
rat ... ALOX5(25290)
General description
Eicosapentaenoic acid is a polyunsaturated fatty acid (PUFAs) and is synthesized from linolenic acid. It is distributed in phospholipid bilayers of the cell membrane, synaptic membranes of the brain and retina. It is obtained majorly from fish oil, seaweed, phytoplankton, and camelina. Being an Omega-3 fatty acid, it shows cis-trans conformations.
Application
cis-5,8,11,14,17-Eicosapentaenoic acid has been used:
- to test pharmacologic effect on steatosis in hepatocytes
- as an analytical standard in Raman spectra measurements to characterize human breast cancer samples
- in lipid peroxidation assay in mouse embryonic fibroblasts and in pre-treatment of cells for cell viability studies
Biochem/physiol Actions
5-Lipoxygenase inhibitor; reduces thromboxane A2 production.
Eicosapentaenoic acid (EPA) is essential for healthy living and alleviates obesity. It decreases the triglyceride levels by modulating very-low-density lipoprotein(VLDL) levels.
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Questo articolo | |||
|---|---|---|---|
| assay ≥99% | assay ≥98.5% (GC) | assay ≥99% (capillary GC) | assay ≥99% |
| form liquid | form - | form film or powder | form - |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility methanol: 50 mg/mL, clear, colorless | solubility - | solubility methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow | solubility - |
| refractive index n20/D 1.4977 (lit.) | refractive index n20/D 1.4977 (lit.) | refractive index - | refractive index n20/D 1.480 (lit.) |
Classe di stoccaggio
10 - Combustible liquids
wgk
WGK 3
flash_point_f
200.1 °F - closed cup
flash_point_c
93.4 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Articoli
Discover Bioactive Small Molecules for Lipid Signaling Research
Che-Hsin Lee et al.
International journal of molecular sciences, 15(6), 10334-10349 (2014-06-12)
Recent studies have shown that free fatty acids are associated with chronic inflammation, which may be involved in vascular injury. The intake of eicosapentaenoic acid (EPA) can decrease cardiovascular disease risks, but the protective mechanisms of EPA on endothelial cells
Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid and their mechanisms of action on apolipoprotein B-containing lipoproteins in humans: a review
Oscarsson J and Hurt-Camejo E
Lipids in Health and Disease, 16(1), 149-149 (2017)
Nutrition and traumatic brain injury: improving acute and subacute health outcomes in military personnel (2011)
Numero articolo commerciale globale
| SKU | GTIN |
|---|---|
| E2011-10MG | 04061833602386 |
| E2011-50MG | 04061833602409 |
| E2011-100MG | 04061838063663 |
| E2011-25MG | 04061833602393 |