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E1631

Sigma-Aldrich

β-Estradiol 17-valerate

≥98% (HPLC), powder

Sinonimo/i:

1,3,5(10)-Estratriene-3,17β-diol 17-pentanote

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About This Item

Formula empirica (notazione di Hill):
C23H32O3
Numero CAS:
979-32-8
Peso molecolare:
356.50
Beilstein:
2480357
Numero CE:
213-559-2
Numero MDL:
MFCD00056541
Codice UNSPSC:
41116107
ID PubChem:
24894423
NACRES:
NA.77

product name

β-Estradiol 17-valerate, ≥98%

Origine biologica

synthetic

Saggio

≥98%

Forma fisica

powder

tecniche

ELISA: suitable

Solubilità

acetone: 25 mg/mL, hazy, colorless

Condizioni di spedizione

ambient

Temperatura di conservazione

room temp

Stringa SMILE

CCCCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C

InChI

1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3
RSEPBGGWRJCQGY-UHFFFAOYSA-N

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Descrizione generale

β-Estradiol 17-valerate is a synthetic estrogen.

Applicazioni

β-Estradiol 17-valerate has been used:
  • in an in-vivo assay, to synchronize the estrus cycle in athymic nude mice, to study the effect of recombinant pigment epithelium-derived factor (rPEDF) on induced ectopic fibroid lesions
  • to study the influence of ovarian hormones on type II cGMP-dependent protein kinase (Prkg2) expression in mice
  • to induce growth of estrogen-dependent tumor cells in athymic nude mice to establish a breast cancer mouse model

Azioni biochim/fisiol

Estradiol valerate is observed to be useful for treating menopausal climacteric symptoms. β-Estradiol 17-valerate is used as a source of 17β-estradiol (E2) in in vitro fertilization, hormone replacement therapy, contraceptive drugs, to study reproductive disorders in animal models. It serves as growth promoter in animal farming. β-Estradiol 17-valerate is also used to culture single-sex population among fish. Studies in rats show that β-Estradiol 17-valerate has negative effects on the estrus cycle pattern.

Pittogrammi

Health hazardEnvironment
GHS08,GHS09

Avvertenze

Warning

Indicazioni di pericolo

H351,H361fd,H362,H410

Classi di pericolo

Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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