C1355

Z-Leu-Glu(O-Me)-His-Asp(O-Me) fluoromethyl ketone trifluoroacetate salt hydrate

≥90%

• Sinonimo/i: Z-LEHD-FMK, Z-LE(OMe)HD(OMe)-FMK
• Formula empirica (notazione di Hill): C₃₂H₄₃FN₆O₁₀ · xC₂HF₃O₂ · yH₂O
• Numero CAS: 210345-04-3
• Peso molecolare: 690.72 (anhydrous free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329774878
• MDL number: MFCD01862609

Proprietà

• assay: ≥90%
• form: film
• storage condition: desiccated
• color: colorless to light brown
• solubility: DMSO: 10 mg/mL, clear
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: COC(=O)CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](CC(=O)OC)C(=O)CF
• InChI: 1S/C32H43FN6O10/c1-19(2)12-24(39-32(46)49-17-20-8-6-5-7-9-20)30(44)36-22(10-11-27(41)47-3)29(43)38-25(13-21-16-34-18-35-21)31(45)37-23(26(40)15-33)14-28(42)48-4/h5-9,16,18-19,22-25H,10-15,17H2,1-4H3,(H,34,35)(H,36,44)(H,37,45)(H,38,43)(H,39,46)/t22-,23-,24-,25-/m0/s1
• InChI key: YXRKBEPGVHOXSV-QORCZRPOSA-N

Descrizione

Application

A cell-permeable inhibitor of caspase-9, which exhibits competitive and irreversible inhibition.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• Classe di stoccaggio: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)