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C0858

Cyclooxygenase 2 human

≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein

Sinonimo/i:

COX-2, Prostaglandin H synthase 2

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Taglio della confezioneSKUDisponibilitàPrezzo
1000 units
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CHF 475.00

Informazioni su questo articolo

UNSPSC Code:
12352204
NACRES:
NA.32
MDL number:
MFCD00071378
Specific activity:
≥8000 units/mg protein
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in insect cells Active recombinant N-terminal His-tagged COX-2 N580A mutant purified from insect cells., expressed in insect cells

CHF 475.00

Per conoscere la disponibilità, visualizza il carrello
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Quality Level

200

recombinant

expressed in insect cells Active recombinant N-terminal His-tagged COX-2 N580A mutant purified from insect cells., expressed in insect cells

assay

≥70% (SDS-PAGE)

form

aqueous solution

specific activity

≥8000 units/mg protein

mol wt

dimer subunit mol wt 70-74 kDa

UniProt accession no.

P35354

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... PTGS2(5743)

General description

KM for arachidonate = 6.5 μM. Exhibits activity and sensitivity to NSAIDs similar to the non-tagged enzyme.

Biochem/physiol Actions

COX-2 catalyzes the conversion of arachidonic acid to prostaglandin H2 (the first step in the biosynthesis of prostaglandins, thromboxanes, and prostacyclins). It is the inducible form of cyclooxygenase, induced by phorbol esters, lipopolysaccharides, and cytokines. COX-2 is upregulated in the neovasculature of malignant tumors. Inhibition of COX-2 with nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with decreased tumor growth.

Physical form

Solution in 80 mM Tris, pH 8.0, with 0.3 mM DDC, 0.01% TWEEN® 20 and 10% glycerol

Other Notes

One unit will consume 1.0 nanomole of oxygen per minute at pH 8 at 37 °C.
Tagged with a six-residue histidine sequence near the N-terminus.

Legal Information

TWEEN is a registered trademark of Croda International PLC

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Questo articolo
SAB5700721AB5118SAB2500267
Cyclooxygenase 2 human ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein

Sigma-Aldrich

C0858

Cyclooxygenase 2 human

Anti-Cox2 antibody produced in rabbit

Sigma-Aldrich

SAB5700721

Anti-Cox2 antibody produced in rabbit

Anti-Cyclooxygenase-2 Antibody Chemicon®, from rabbit

Sigma-Aldrich

AB5118

Anti-Cyclooxygenase-2 Antibody

Anti-COX2/PTGS2 antibody produced in goat affinity isolated antibody, buffered aqueous solution

Sigma-Aldrich

SAB2500267

Anti-COX2/PTGS2 antibody produced in goat

specific activity

≥8000 units/mg protein

specific activity

-

specific activity

-

specific activity

-

Gene Information

human ... PTGS2(5743)

Gene Information

human ... PTGS2(5743)

Gene Information

human ... PTGS2(5743)

Gene Information

human ... PTGS2(5743)

assay

≥70% (SDS-PAGE)

assay

-

assay

-

assay

-

form

aqueous solution

form

buffered aqueous solution

form

-

form

buffered aqueous solution

recombinant

expressed in insect cells Active recombinant N-terminal His-tagged COX-2 N580A mutant purified from insect cells.

recombinant

-

recombinant

-

recombinant

-

storage temp.

−70°C

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

Classe di stoccaggio

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
0000262007
SLCR2924
0000262007
SLCM9525
SLCP9213

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Numero articolo commerciale globale

SKUGTIN
C0858-1000UN04061838254863

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