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Merck
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Documenti fondamentali

B9688

Sigma-Aldrich

Pizotifen

≥98% (HPLC)

Sinonimo/i:

Pizotifen, Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine

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10 MG
CHF 88.70
50 MG
CHF 351.00

CHF 88.70


Spedizione prevista il28 maggio 2025


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Cambia visualizzazione
10 MG
CHF 88.70
50 MG
CHF 351.00

About This Item

Formula empirica (notazione di Hill):
C19H21NS
Numero CAS:
Peso molecolare:
295.44
Numero CE:
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77

CHF 88.70


Spedizione prevista il28 maggio 2025


Richiedi un ordine bulk

Saggio

≥98% (HPLC)

Stato

powder

Solubilità

DMSO: ≥8 mg/mL

Ideatore

Novartis

Temperatura di conservazione

room temp

Stringa SMILE

CN1CCC(\CC1)=C2\c3ccccc3CCc4sccc24

InChI

1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
FIADGNVRKBPQEU-UHFFFAOYSA-N

Categorie correlate

Azioni biochim/fisiol

Pizotifen is a Serotonin antagonist used for prophylaxis of migraine
Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.

Caratteristiche e vantaggi

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pittogrammi

Health hazardExclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Repr. 2

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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Joy A Weydert et al.
Pediatrics, 111(1), e1-11 (2003-01-02)
To conduct a systematic review of evaluated treatments for recurrent abdominal pain (RAP) in children. Online bibliographic databases were searched for the terms "recurrent abdominal pain," "functional abdominal pain," "children," or "alternative therapies" in articles classified as randomized controlled trials.
Do pizotifen or propranolol reduce the frequency of migraine headache?
N Barnes et al.
Archives of disease in childhood, 89(7), 684-685 (2004-06-24)
Ying Jiang et al.
Experimental and therapeutic medicine, 19(2), 817-824 (2020-02-06)
Gastric cancer is the fifth most common malignancy and the third highest cause of cancer-associated mortality worldwide. Therefore, research on the pathogenesis of gastric cancer is of utmost importance. It has been reported that aberrant activation of the Wnt/β-catenin signaling
Rachel Ej Besser et al.
Acta paediatrica (Oslo, Norway : 1992), 94(12), 1860-1862 (2006-01-20)
We report a case of two siblings with Raynaud phenomena and migraine, whose symptoms were successfully treated with pizotifen. To our knowledge, this is the first case documenting the association between Raynaud phenomena and migraine in two siblings with a
A Huertas-Ceballos et al.
The Cochrane database of systematic reviews, (1)(1), CD003017-CD003017 (2008-02-07)
Between 4% and 25% of school-age children complain of recurrent abdominal pain (RAP) of sufficient severity to interfere with daily activities. For the majority no organic cause for their pain can be found on physical examination or investigation and although

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