A9451

Aristolochic acid I sodium salt

powder, ≥97%

• Sinonimo/i: Aristolochic acid sodium salt
• Formula empirica (notazione di Hill): C₁₇H₁₀NNaO₇
• Numero CAS: 10190-99-5
• Peso molecolare: 363.25
• NACRES: NA.77
• PubChem Substance ID: 24891454
• UNSPSC Code: 12352202
• EC Number: 233-463-4
• MDL number: MFCD00210760
• Assay: ≥97%
• Form: powder
• Solubility: H₂O: 50 mg/mL

Proprietà

• Quality Segment: 200
• assay: ≥97%
• form: powder
• solubility: H₂O: 50 mg/mL
• SMILES string: [Na+].COc1cccc2c1cc([N+]([O-])=O)c3c(cc4OCOc4c23)C([O-])=O
• InChI: 1S/C17H11NO7.Na/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13;/h2-6H,7H2,1H3,(H,19,20);/q;+1/p-1
• InChI key: BQVOPWJSBBMGBR-UHFFFAOYSA-M

Descrizione

Biochem/physiol Actions

Component of some Chinese herbal medicines, and responsible for their nephrotoxicity. Prodrug activated by reduction of the nitro group to an amine, which forms cytotoxic DNA adducts.

Informazioni sulla sicurezza

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311 + H331,H351
• pcodes: P202 - P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2
• Classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges