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Merck
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Documenti

94121

Sigma-Aldrich

Baicalin

≥99.0% (HPLC)

Sinonimo/i:

5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid, Baicalein 7-O-β-D-glucuronide

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About This Item

Formula empirica (notazione di Hill):
C21H18O11
Numero CAS:
21967-41-9
Peso molecolare:
446.36
Numero MDL:
MFCD00134418
Codice UNSPSC:
12352201
ID PubChem:
329770302

Origine biologica

synthetic

Saggio

≥99.0% (HPLC)

Forma fisica

solid

Attività ottica

[α]/D -83±3°, c = 1 in DMSO

tecniche

HPLC: suitable

Punto di fusione

202-205 °C (dec.) (lit.)

Stringa SMILE

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccccc4

InChI

1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1
IKIIZLYTISPENI-ZFORQUDYSA-N

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Applicazioni

Baicalin, a flavonoid compound with potential therapeutic value, is used to study its anti-inflammatory and anti-oxidant properties. Baicalin is also used to study its potential as an anti-sepsis agent.

Azioni biochim/fisiol

Baicalin, a component of Traditional Chinese Medicine (TCM), is a flavonoid component found in several species in the genus Scutellaria. Baicalin is an inhibitor of prolyl endopeptidases.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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T B Ng et al.
Life sciences, 66(8), 709-723 (2000-02-19)
A variety of flavonoids, lignans, an alkaloid, a bisbenzyl, coumarins and terpenes isolated from Chinese herbs was tested for antioxidant activity as reflected in the ability to inhibit lipid peroxidation in rat brain and kidney homogenates and rat erythrocyte hemolysis.
Zhenhua Pei et al.
Journal of periodontology, 85(9), 1283-1290 (2014-01-31)
Periodontitis is the most common cause of tooth loss in adults. Periodontal ligament cell (PLC)-based therapy is considered one of the most promising methods in periodontal tissue regeneration. The traditional Chinese medicine baicalin has been shown to possess antimicrobial and
Z Gao et al.
Biochimica et biophysica acta, 1472(3), 643-650 (1999-11-24)
Free radical scavenging and antioxidant activities of baicalein, baicalin, wogonin and wogonoside, the four major flavonoids in the radix of Scutellaria baicalensis Georgi, were examined in different systems. ESR results showed that baicalein and baicalin scavenged hydroxyl radical, DPPH radical
Xi-Ping Zhang et al.
World journal of gastroenterology, 13(38), 5079-5089 (2007-09-19)
To investigate the protective effects and mechanisms of Baicalin and octreotide on renal injury of rats with severe acute pancreatitis (SAP). One hundred and eighty SD rats were randomly assigned to the model group, Baicalin-treated group, octreotide-treated group and sham
Miao Lin et al.
BMC complementary and alternative medicine, 14, 19-19 (2014-01-15)
Renal ischemia-reperfusion injury (IRI) increases the rates of acute kidney failure, delayed graft function, and early mortality after kidney transplantation. The pathophysiology involved includes oxidative stress, mitochondrial dysfunction, and immune-mediated injury. The anti-oxidation, anti-apoptosis, and anti-inflammation properties of baicalin, a
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