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69554

Peptidoglycan from Bacillus subtilis

Sinonimo/i:

PGN

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Taglio della confezioneSKUDisponibilitàPrezzo
10 mg
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CHF 212.00

Informazioni su questo articolo

UNSPSC Code:
41116134
NACRES:
NA.21
MDL number:

CHF 212.00


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form

solid

Quality Level

storage temp.

−20°C

General description

Peptidoglycan.is a biopolymer that is a major component of the cell walls of Gram-positive bacteria. Peptidoglycan consists of a carbohydrate backbone of alternating units of N-acetyl glucosamine and N-acetyl muramic acid and is modified with both D- and L-amino acids. N-Acetyl muramic acid residues are cross-linked with oligopeptides. The terminal peptide is D-alanine although other amino acids are present as D-isomers.

Application

Peptidoglycan may be used for the activity estimation of lytic enzymes (e.g. lyticase). It is recommended to use a peptidoglycan concentration of 0.15-3 μg/ml in water or buffer and measuring at 450 nm. The peptidoglycan is not soluble but produces a suspension in water.
Peptidoglycan activates the Toll-like receptor 2 (TLR2), present in mammalian cells for the stimulation of lymphocytes. It may also function as an antagonist of Poly (I:C).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Questo articolo
SMB00288G500250845
Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

form

solid

form

lyophilized powder

form

-

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C


Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articoli

Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.


Yichao Xie et al.
Fish & shellfish immunology, 106, 384-392 (2020-08-11)
Antimicrobial peptide (AMP) is a crucial component of the innate immune system in crustaceans. In mud crab, Scylla paramamosain, a commercially important species, a glycine-rich antimicrobial peptide (Spgly-AMP) gene was newly identified and putatively encoded a 26aa signal peptide and
Christian Stelter et al.
PloS one, 6(6), e20749-e20749 (2011-06-23)
Intestinal inflammation induces alterations of the gut microbiota and promotes overgrowth of the enteric pathogen Salmonella enterica by largely unknown mechanisms. Here, we identified a host factor involved in this process. Specifically, the C-type lectin RegIIIβ is strongly upregulated during
Qian Zhu et al.
Fish & shellfish immunology, 100, 9-17 (2020-03-05)
Interleukin (IL)-11 is a multifunctional cytokine that exerts a series of important immunomodulatory effects and exists in many tissues and cells. A 1106-bp nucleotide sequence representing the complete cDNA of IL-11 was obtained from large yellow croaker (Larimichthys crocea), containing



Numero articolo commerciale globale

SKUGTIN
69554-10MG-F04061833278079

Questions

1–5 of 5 Questions  
  1. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  2. What is the method of preparation of Product 69554, Peptidoglycan?

    1 answer
    1. Peptidoglycan is made by fermentation and so it is from vegetative cell bacteria.  Peptidoglycan is from strain DSM 10.

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  3. Is Product 69554, Peptidoglycan, Gram positive or Gram negative?

    1 answer
    1. Peptidoglycan is Gram positive.

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  4. What is the solubility of Product 69554, Peptidoglycan?

    1 answer
    1. Peptidoglycans are insoluble in all solvents.  To increase the recovery of solubility, let the peptidoglycan soak in an aqueous buffer for several hours or overnight.

      Helpful?

  5. What is the molecular weight of Product 69554, Peptidoglycan?

    1 answer
    1. Unfortunately, we have no references reporting the molecular weight of peptidoglycan.  Because it is not soluble without destroying the original structure, the molecular weight can not be determined by suitable analytical methods (GPC, viscosity, light scattering).

      Helpful?

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