DISBAC2(3), Voltage Sensitive Probe

Name: DISBAC2(3), Voltage Sensitive Probe
Brand: SIGMA
Price: 575 CHF

≥98% (HPLC)

Sinonimo/i:

5-[3-(1,3-Diethylhexahydro-4,6-dioxo-2-thioxo-5-pyrimidinyl)-2-propen-1-ylidene]-1,3-diethyldihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione, Bis(1,3-diethylthiobarbituric acid)trimethine oxonol

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1 MG

CHF 575.00

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Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₁₉H₂₄N₄O₄S₂

Numero CAS:

47623-98-3

Peso molecolare:

436.55

UNSPSC Code:

12352108

NACRES:

NA.32

PubChem Substance ID:

329756577

EC Number:

256-325-5

Beilstein/REAXYS Number:

1232950

MDL number:

MFCD07437858

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Quality Level

100

assay

≥98% (HPLC)

fluorescence

λ_ex 535 nm; λ_em 560 nm in DMSO

suitability

complies for Infrared spectrum

storage temp.

−20°C

SMILES string

CCN1C(=O)C(\C=C\C=C2\C(=O)N(CC)C(=S)N(CC)C2=O)C(=O)N(CC)C1=S

InChI

1S/C19H24N4O4S2/c1-5-20-14(24)12(15(25)21(6-2)18(20)28)10-9-11-13-16(26)22(7-3)19(29)23(8-4)17(13)27/h9-12H,5-8H2,1-4H3/b10-9+

InChI key

VJYNRXFXHKIGLT-MDZDMXLPSA-N

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Questo articolo	930709	SML2683	901099
Sigma-Aldrich 44977 DISBAC2(3), Voltage Sensitive Probe	Sigma-Aldrich 930709 Pomalidomide-piperazine-propanoic acid	Sigma-Aldrich SML2683 dBET6	Sigma-Aldrich 901099 PBDB-T
suitability complies for Infrared spectrum	suitability -	suitability -	suitability -
fluorescence λ_ex 535 nm; λ_em 560 nm in DMSO	fluorescence -	fluorescence -	fluorescence -
storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C	storage temp. -
Quality Level 100	Quality Level 100	Quality Level -	Quality Level 100
assay ≥98% (HPLC)	assay ≥95.0%	assay ≥98% (HPLC)	assay -

Application

DISBAC2(3), Voltage Sensitive Probe is used for single-cell fluorescence imaging of transmembrane conductance and potential change.

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Measurement of membrane potential of endothelial cells in single perfused microvessels.

P He et al.

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The membrane potential is an important modulator of calcium ion flux into endothelial cells of venular microvessels. We developed a method to measure the membrane potential of endothelial cells forming the walls of individually perfused microvessels under the same experimental

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ATP-independent membrane depolarization with ischemia in the oxygen-ventilated isolated rat lung.

A B Al-Mehdi et al.

American journal of respiratory cell and molecular biology, 18(5), 653-661 (1998-06-06)

We hypothesize that lung ischemic injury is related to cessation of flow leading to endothelial cell membrane depolarization and activation of oxidant-generating systems. Cell membrane potential was assessed in isolated, oxygen ventilated, Krebs-Ringer bicarbonate buffer-dextran-perfused rat lungs by lung surface

Effect of ion composition on the changes in membrane potential induced with several stimuli in rat mast cells.

A G Cabado et al.

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We studied, in different ionic conditions, the effect of various agents on the membrane potential of rat peritoneal mast cells using the fluorescent probe bisoxonol. Ouabain and ionophore A23187 lead to a fast depolarization of the plasma membrane of mast

Real-time and high throughput monitoring of cAMP in live cells using a fluorescent membrane potential-sensitive dye.

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Adenosine-3',5'-cyclic monophosphate (cAMP) conveys the signals from G-protein coupled receptors (GPCRs) and regulates a variety of downstream cellular events. However, there are few robust assays available for measuring cAMP in live cells. Most of the existing cAMP assays require cell

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Numero articolo commerciale globale

SKU	GTIN
44977-1MG	04061823367226

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DISBAC2(3), Voltage Sensitive Probe