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E3876

N-etilmaleimide

crystalline, ≥98% (HPLC)

Sinonimo/i:

NEM

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Taglio della confezioneSKUDisponibilitàPrezzo
5 g
Per conoscere la disponibilità, visualizza il carrello
CHF 162.00
25 g
Per conoscere la disponibilità, visualizza il carrello
CHF 541.00
100 g
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CHF 1’590.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C6H7NO2
Numero CAS:
Peso molecolare:
125.13
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
EC Number:
204-892-4
Beilstein/REAXYS Number:
112448
MDL number:

CHF 162.00


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biological source

synthetic (organic)

Quality Segment

assay

≥98% (HPLC)

form

crystalline

storage condition

(Tightly closed. Dry. Keep in a well-ventilated place. )

technique(s)

activity assay: suitable, co-immunoprecipitation (co-IP): suitable, immunoblotting: suitable

color

white to faint yellow

bp

210 °C (lit.)

mp

43-46 °C (lit.)

solubility

ethanol: 50 mg/mL, clear to slightly hazy, colorless to faint yellow or tan

suitability

suitable for Western blot

application(s)

life science and biopharma

storage temp.

2-8°C

SMILES string

CCN1C(=O)C=CC1=O

InChI

1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3

InChI key

HDFGOPSGAURCEO-UHFFFAOYSA-N

Application

Reagente per la modificazione covalente dei residui di cisteina nelle proteine.

Biochem/physiol Actions

Agente alchilante sulfidrilico che inattiva la isocitrato deidrogenasi NADP-dipendente e diverse endonucleasi.
Incrementa la corrente dai canali M nativi nei neuroni simpatici e induce l′apertura dei canali KCNQ2, KCNQ4 e KCNQ5.

Preparation Note

La soluzione di NEM in etanolo at 50 mg/mL è limpida. NEM si dissolve in acqua (>50 mg in 4 mL); tuttavia le soluzioni acquose sono instabili. La velocità dell′idrolisi è di pseudo primo ordine e dipende notevolmente dal pH.

Other Notes

Per ulteriori informazioni sulla nostra gamma di Composti biochimici, compilare questo modulo.

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Questo articolo
E1271C13408WH0056479M1
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

98%

assay

-

biological source

synthetic (organic)

biological source

-

biological source

synthetic (organic)

biological source

mouse

Gene Information

human ... KCNQ2(3785), KCNQ4(9132), KCNQ5(56479), SLC6A3(6531), SLC6A4(6532)

Gene Information

human ... SLC6A3(6531), SLC6A4(6532)

Gene Information

-

Gene Information

human ... KCNQ5(56479)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

crystalline

form

-

form

crystalline powder, powder or crystals

form

buffered aqueous solution

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C


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pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

Classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

163.2 °F - closed cup

flash_point_c

72.9 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Contenuto correlato






Numero articolo commerciale globale

SKUGTIN
E3876-5G04061835518098
E3876-25G04061835544417
E3876-100G04061833603437

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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