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32476

Selamectin

VETRANAL®, analytical standard

Sinonimo/i:

(5Z)-25-Cyclohexyl-4′-O-de(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-demethoxy-25-de(1-methylpropyl)-22,23-dihydro-5-(hydroxyimino)avermectin A1a

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Taglio della confezioneSKUDisponibilitàPrezzo
10 mg
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CHF 461.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C43H63NO11
Numero CAS:
Peso molecolare:
769.96
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

CHF 461.00


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grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O/N=C1[C@]2([H])[C@]3(O)[C@@](C(O[C@@H]4C[C@]5(O[C@@](C/C=C(C)/[C@@H](O[C@]6([H])C[C@@H]([C@@H](O)[C@H](C)O6)OC)[C@@H](C)/C=C/C=C3\CO2)([H])C4)O[C@H](C7CCCCC7)[C@@H](C)CC5)=O)([H])C=C\1C

InChI

1S/C43H63NO11/c1-24-11-10-14-30-23-50-40-36(44-48)27(4)19-33(43(30,40)47)41(46)52-32-20-31(16-15-25(2)38(24)53-35-21-34(49-6)37(45)28(5)51-35)54-42(22-32)18-17-26(3)39(55-42)29-12-8-7-9-13-29/h10-11,14-15,19,24,26,28-29,31-35,37-40,45,47-48H,7-9,12-13,16-18,20-23H2,1-6H3/b11-10+,25-15+,30-14+,44-36-/t24-,26-,28-,31+,32-,33-,34-,35-,37-,38-,39-,40+,42+,43+/m0/s1

InChI key

AFJYYKSVHJGXSN-XHKIUTQPSA-N

General description

Selamectin (25-cyclohexyl-25-de(1-methylpropyl)-5-deoxy-22,23-dihydro-5-(hydroxyimino)-avermectin B1 monosaccharide) is a novel endectocide. It is an anti-parasitic agent and has a unique combination of safety and efficacy both in cats and dogs following both topical and oral administration. It prevents ticks and fleas, immature heartworms, ascarids and intestinal hookworms. It can be easily tolerated even at higher dosages than 22,23-dihydroavermectin B1a (DHAVM).[1]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Questo articolo
SML26631611729Y0000814
Selamectin VETRANAL®, analytical standard

Supelco

32476

Selamectin

Selamectin ≥98% (HPLC)

Sigma-Aldrich

SML2663

Selamectin

Selamectin United States Pharmacopeia (USP) Reference Standard

USP

1611729

Selamectin

vibrant-m

Y0000814

Selamectin

grade

analytical standard

grade

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

format

neat

format

-

format

neat

format

neat

product line

VETRANAL®

product line

-

product line

-

product line

-

application(s)

forensics and toxicology
pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical

application(s)

pharmaceutical (small molecule)

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-

storage temp.

2-8°C

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-


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hcodes

Hazard Classifications

Aquatic Chronic 4

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3



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Chandan Seth et al.
PloS one, 11(12), e0168170-e0168170 (2016-12-16)
The WNT-TCF signaling pathway participates in adult tissue homeostasis and repair, and is hyperactive in a number of human diseases including cancers of the colon. Whereas to date there are no antagonists approved for patient use, a potential problem for
Selamectin: a novel broad-spectrum endectocide for dogs and cats
Bishop, B. F., et al.
Veterinary Parasitology, 91 (3), 163-176 (2000)
Alice Melotti et al.
EMBO molecular medicine, 6(10), 1263-1278 (2014-08-22)
Constitutive activation of canonical WNT-TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT-TCF antagonists in clinical use. We have performed a repositioning screen for WNT-TCF response blockers aiming to recapitulate the genetic



Numero articolo commerciale globale

SKUGTIN
32476-10MG04061826711736

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