16633

1-(4-Methoxyphenyl)-3-(4-tert-butylphenyl)-1,3-propanedione

analytical standard

• Sinonimo/i: Avobenzone, Butylmethoxydibenzoylmethane
• Formula empirica (notazione di Hill): C₂₀H₂₂O₃
• Numero CAS: 70356-09-1
• Peso molecolare: 310.39
• Numero CE: 274-581-6
• Numero MDL: MFCD00210252
• Codice UNSPSC: 41116107
• ID PubChem: 329751311
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Saggio: ≥99.0% (GC)
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Punto di fusione: 81-84 °C
• applicazioni: cleaning products; cosmetics; environmental; food and beverages; personal care
• Formato: neat
• Stringa SMILE: COc1ccc(cc1)C(=O)CC(=O)c2ccc(cc2)C(C)(C)C
• InChI: 1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3; XNEFYCZVKIDDMS-UHFFFAOYSA-N

Descrizione

Descrizione generale

Avobenzone is an UVA filter. It is used in sunscreen lotions and cosmetic formulations. It has maximum absorption at ca 340–350 nm, decreasing under UV irradiation resulting in loss of the UVA protecting effect. Its photostability is very sensitive as it is stable in polar protic solvent and is photolabile in nonpolar solvents.

Applicazioni

Avobenzone may be used as an analytical reference standard for the quantification of the analyte in the following:

• Sunscreen formulations using reversed-phase high-performance liquid chromatography with diode array detection (RP-HPLC-DAD).[1]
• Freshwater, saline water samples,[2] rat plasma and skin layers[3] using liquid chromatography-positive electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) in multiple reaction monitoring mode (MRM).

Avobenzone may be used to study the photophysical characteristics, photosensitizing activity of a blocked diketo form derived from 4-tert-butyl-4′-methoxydibenzoylmethane (BM-DBM).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Informazioni sulla sicurezza

• Indicazioni di pericolo: H413
• Consigli di prudenza: P273 - P501
• Classi di pericolo: Aquatic Chronic 4
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Dispositivi di protezione individuale: Eyeshields, Gloves