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09236

Supelco

β-Amyrin

analytical standard

Sinonimo/i:

β-Amyrenol, Olean-12-en-3β-ol

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About This Item

Formula empirica (notazione di Hill):
C30H50O
Numero CAS:
559-70-6
Peso molecolare:
426.72
Beilstein:
2063468
Numero CE:
209-204-6
Numero MDL:
MFCD00017381
Codice UNSPSC:
85151701
ID PubChem:
329748744
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Saggio

≥98.5% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

food and beverages

Formato

neat

Stringa SMILE

[H][C@@]12CC(C)(C)CC[C@]1(C)CC[C@]3(C)C2=CC[C@]4([H])[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C

InChI

1S/C30H50O/c1-25(2)15-16-27(5)17-18-29(7)20(21(27)19-25)9-10-23-28(6)13-12-24(31)26(3,4)22(28)11-14-30(23,29)8/h9,21-24,31H,10-19H2,1-8H3/t21-,22-,23+,24-,27+,28-,29+,30+/m0/s1
JFSHUTJDVKUMTJ-QHPUVITPSA-N

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Categorie correlate

Descrizione generale

β-Amyrin belongs to the group of naturally occurring pentacyclic triterpenes, known for its anti-inflammatory, anti-microbial, anti-oxidative, and chemoprotective properties.

Applicazioni

This analytical standard can also be used as follows:

  • Development and validation of two high-performance thin layer chromatography (HPTLC) methods to quantify four biomarkers— β-amyrin, β-sitosterol, lupeol, and ursolic acid in the ethanol extract of G. senegalensis leaves
  • Analysis of methanol extracts of leaf samples collected from five Ficus species by a novel HPTLC densitometric method, for the determination of β-amyrin, validated according to the International Conference on Harmonization (ICH) guidelines
  • Quantification of β-amyrin in the ethanolic extracts collected from two Maytenus species, M. obscura and M. parviflora by a validated HPTLC-densitometric method
  • Secondary metabolite profiling of various plant parts collected from 82 plants belonging to 21 different cannabis strains using gas chromatography-mass spectrometry (GC-MS) for sterols and terpenoids (mono-, sesqui-, tri-), and high-performance liquid chromatography (HPLC) with UV and mass spectrometric (MS) detection for flavonoids

Azioni biochim/fisiol

Triterpene that has broad-spectrum analgesic properties for which the underlying mechanism is poorly understood.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Consigli di prudenza

P301 + P312 + P330

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
BCCL5090
BCCL2703
BCCK7288
BCCH8757
BCCJ7164

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Lupeol phyproof® Reference Substance

PHL89722

Lupeol

α-Spinasterol ≥98% (HPLC)

Sigma-Aldrich

SML2232

α-Spinasterol

(3S)-2,3-Oxidosqualene ≥97.5% (HPLC)

Sigma-Aldrich

41719

(3S)-2,3-Oxidosqualene

Betulin ≥98%

Sigma-Aldrich

B9757

Betulin

Oleanolic acid ≥97%

Sigma-Aldrich

O5504

Oleanolic acid

Hederagenin ≥97% (HPLC)

Sigma-Aldrich

H3916

Hederagenin

Erythrodiol analytical standard

Supelco

09258

Erythrodiol

β-Amyrin induces angiogenesis in vascular endothelial cells through the Akt/endothelial nitric oxide synthase signaling pathway.
Ishii M, et al.
Biochemical and Biophysical Research Communications, 467(4), 676-682 (2015)
Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography.
Martelanc M, et al.
Journal of Chromatography A, 1216(38), 6662-6670 (2009)
Miao Wu et al.
Genes, 11(2) (2020-02-14)
Polyploid plants are more often invasive species than their diploid counterparts. As the invasiveness of a species is often linked to its production of allelopathic compounds, we hypothesize that differences in invasive ability between cytotypes may be due to their
Hikaru Seki et al.
The Plant cell, 23(11), 4112-4123 (2011-12-01)
Glycyrrhizin, a triterpenoid saponin derived from the underground parts of Glycyrrhiza plants (licorice), has several pharmacological activities and is also used worldwide as a natural sweetener. The biosynthesis of glycyrrhizin involves the initial cyclization of 2,3-oxidosqualene to the triterpene skeleton
Kathryn A B Simão da Silva et al.
Pain, 152(8), 1872-1887 (2011-05-31)
In this study, we report that α,β-amyrin, a plant-derived pentacyclic triterpene, reduced persistent inflammatory and neuropathic hyperalgesia in mice by a direct activation of the CB(1) and CB(2) cannabinoid receptors (CB(1)R and CB(2)R). The oral treatment with α,β-amyrin (30 mg/kg)
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