08511

Curcumin

analytical standard

• Sinonimo/i: (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, Diferuloylmethane, Diferulylmethane, Natural Yellow 3
• Formula condensata: [HOC₆H₃(OCH₃)CH=CHCO]₂CH₂
• Numero CAS: 458-37-7
• Peso molecolare: 368.38
• Colour Index: 75300
• Beilstein: 2306965
• Numero CE: 207-280-5
• Numero MDL: MFCD00008365
• Codice UNSPSC: 85151701
• ID PubChem: 329748594
• Numero E: E100
• NACRES: NA.24

Proprietà

• Grado: analytical standard
• Livello qualitativo: 100
• Densità del vapore: 13 (vs air)
• Saggio: ≥98.0% (HPLC)
• Forma fisica: powder
• Durata: limited shelf life, expiry date on the label
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• applicazioni: cleaning products; cosmetics; food and beverages; personal care
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)c(OC)c2)ccc1O
• InChI: 1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+; VFLDPWHFBUODDF-FCXRPNKRSA-N

Descrizione

Descrizione generale

Curcumin is an anti-inflammatory agent extracted from the roots of Curcuma longa Linn.

Applicazioni

Curcumin may be used as a reference standard for the determination of curcumin in rat plasma by high-performance liquid chromatography method.

Azioni biochim/fisiol

A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

This compound is commonly found in plants of the genus: curcuma

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable