MABC140

Anti-ARC Antibody, clone 6F9.1

clone 6F9.1, from mouse

• Sinonimo/i: Activity-regulated cytoskeleton-associated protein, ARC/ARG3.1, Activity-regulated gene 3.1 protein homolog, Arg3.1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: 6F9.1, monoclonal
• Reattività contro le specie: human
• tecniche: immunohistochemistry: suitable (paraffin); western blot: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_056008
• N° accesso UniProt: Q7LC44
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ARC(23237)

Descrizione

Descrizione generale

Activity-regulated cytoskeleton-associated protein (ARC), also known as Activity-regulated gene 3.1 protein homolog (ARG3.1), plays an important role in synaptic plasticity and the formation of long-term memory. ARC is enriched in the postsynaptic density of dendritic spines and regulates endocytosis of AMPA receptors in response to synaptic activity and is required for homeostatic synaptic scaling of AMPA receptors. ARC also plays a role in the regulation of cell morphology, cytoskeletal organization, stress fiber dynamics, and cell migration.

Immunogeno

GST-tagged recombinant protein corresponding to human ARC.

Applicazioni

Anti-ARC Antibody, clone 6F9.1 is a highly specific mouse monoclonal antibody, that targets ARC & has been tested in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected ARC in human brain tissue.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Qualità

Evaluated by Western Blotting in human hippocampus tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected ARC in 200 µg of human hippocampus tissue lysate.

Descrizione del bersaglio

~ 45 kDa observed

Stato fisico

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Human hippocampus tissue lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable