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3301

17β-Estradiol

≥97% (HPLC), solid, estrogenic hormone, Calbiochem

17β-Estradiol

Sinonimo/i:

17β-Estradiol, 17 beta Estradiol

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Taglio della confezioneSKUDisponibilitàPrezzo
1 g

Spedizione prevista per OGGIdaBuchs

CHF 134.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C18H24O2
Numero CAS:
Peso molecolare:
272.38
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥97% (by assay)
Form:
solid
Quality level:
Storage condition:
OK to freeze

CHF 134.00


Spedizione prevista per OGGIDettagli


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Nome del prodotto

17β-Estradiol, Most potent mammalian estrogenic hormone.

Quality Level

description

RTECS - KG2975000
Merck USA index - 14, 3703

assay

≥97% (by assay)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to off-white

solubility

ethanol: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

O[C@@H]1[C@@]2([C@H]([C@H]3[C@H](CC2)c4c(cc(cc4)O)CC3)CC1)C

InChI

1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

InChI key

VOXZDWNPVJITMN-ZBRFXRBCSA-N

General description

17β-Estradiol is a potent estrogen, a steroid hormone, involved in reproductive and endocrine functions in mammals. It binds to estrogen receptors (ERα and ERβ) to regulate gene expression, influencing reproductive functions such as the proliferation of the uterine endometrium, ovulation, and maintenance of pregnancy. Additionally, 17β-Estradiol is involved in modulating metabolic processes, including lipid metabolism and insulin sensitivity, and exerts neuroprotective effects in the central nervous system.

Application

17β-Estradiol has been used to treat primary rat cortical neurons, to investigate its effects on neuronal responses to interleukin (IL)-6 and soluble IL-6 receptor treatment.[1] It has also been administered subcutaneously to ovariectomized female mice to investigate its effects on Crhr1 and Esr1 mRNA expression in the nucleus accumbens.[2]

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)


pictograms

Health hazardEnvironment

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A

Classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificati d'analisi (COA)

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Numero articolo commerciale globale

SKUGTIN
155578-5G04061838742087
155578-25G04061831828535
3301-1GM07790788049201

Questions

  1. how long can you store the product at 4C after dissolving the product in ethanol ?

    1 answer
    1. When stored refrigerated at 2 - 8°C, de-gassed stock solutions are stable for up to 6 months. Alternatively, stock solutions may be stored frozen at -20°C for up to 3 months. Avoid repeated freeze/thaw cycles.

      Helpful?

Reviews

Active Filters

  1. Bucharest
    • Reviews 2
    • Votes 4
    4 out of 5 stars.

    fit for the purpose

    Low solubility in water, as known. Would recommend the Cyclodextrin-encapsulated form (E4389) for application that require only water or media as solvent.

    Helpful?