04-478
Anti-phospho-STAT1 (Ser 727) Antibody, clone 12C5
clone 12C5, Upstate®, from mouse
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About This Item
Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Prodotti consigliati
Origine biologica
mouse
Livello qualitativo
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
12C5, monoclonal
Reattività contro le specie
human
Produttore/marchio commerciale
Upstate®
tecniche
ELISA: suitable
western blot: suitable
Isotipo
IgG1
N° accesso NCBI
N° accesso UniProt
Condizioni di spedizione
wet ice
modifica post-traduzionali bersaglio
phosphorylation (pSer727)
Informazioni sul gene
human ... STAT1(6772)
Specificità
Recognizes phosphorylated domain of STAT1 on Serine727
Immunogeno
KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Serine727 on phosphorylated STAT1
Applicazioni
Anti-phospho-STAT1 (Ser 727) Antibody, clone 12C5 is a Mouse Monoclonal Antibody for detection of phospho-STAT1 (Ser 727) also known as signal transducer & activator of transcription 1 & has been tested in ELISA & WB.
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Transcription Factors
Qualità
Routinely evaluated by immunoblot.
Descrizione del bersaglio
92 kDa
Stato fisico
Format: Purified
In 1 mL of PBS containing 0.09% sodium azide, PEG, sucrose, and 50% glycerol.
Subsequent thiophilic adsorption and size exclusion chromatography
Stoccaggio e stabilità
2 years at -20°C from date of shipment. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance.
Lee, Y K, et al.
Leukemia, 19, 513-523 (2005)
Rico K H Lo et al.
Cellular signalling, 18(3), 307-317 (2005-06-28)
The ability of the human prostacyclin receptor (hIP) to regulate the activities of signal transducers and activators of transcription (STATs) has not yet been documented. In the present study, we have delineated the mechanism by which hIP induces STAT3 phosphorylations
H Nguyen et al.
The Journal of biological chemistry, 276(36), 33361-33368 (2001-07-05)
STAT1 must be phosphorylated on serine 727 to be fully active in transcription. We show that phosphatidylinositol 3-kinase (PI3K) and its effector kinase Akt play an important role in the serine phosphorylation of STAT1 and in the activation of gene
Christopher P Gayer et al.
The Journal of biological chemistry, 284(4), 2001-2011 (2008-12-03)
The intestinal epithelium is repetitively deformed by shear, peristalsis, and villous motility. Such repetitive deformation stimulates the proliferation of intestinal epithelial cells on collagen or laminin substrates via ERK, but the upstream mediators of this effect are poorly understood. We
Rama S Kota et al.
The Journal of biological chemistry, 280(35), 31076-31084 (2005-07-05)
Lipoprotein lipase (LPL) is a key enzyme in the hydrolysis of triglyceride-rich lipoproteins. In vascular diseases, such as atherosclerosis, inflammation plays an important role in the pathogenesis of the disease. We examined the role of LPL in modulating tumor necrosis
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