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Merck
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Documenti fondamentali

B0515

Sigma-Aldrich

Betamethasone 17-valerate

Sinonimo/i:

1,4-Pregnadiene-11β,17α,21-triol-9α-fluoro-16β-methyl-3,20-dione 17-valerate, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17-valerate, 9α-Fluoro-16β-methylprednisolone 17-valerate, Betnovate

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25 MG
CHF 88.60
100 MG
CHF 251.00
500 MG
CHF 756.00

CHF 88.60


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25 MG
CHF 88.60
100 MG
CHF 251.00
500 MG
CHF 756.00

About This Item

Formula empirica (notazione di Hill):
C27H37FO6
Numero CAS:
Peso molecolare:
476.58
Beilstein:
4240001
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77

CHF 88.60


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Stato

powder

Ideatore

Schering Plough

Temperatura di conservazione

2-8°C

Stringa SMILE

CCCCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)CO

InChI

1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19?,20?,21-,24-,25-,26-,27-/m0/s1
SNHRLVCMMWUAJD-QDHNOTTGSA-N

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Azioni biochim/fisiol

Betamethasone 17-valerate is a synthetic glucocorticoid. It exhibitstherapeutic effects against various allergic and inflammatory skin diseases.[1] Betamethasone 17-valerate also possesses anti-inflammatory properties.[2]

Caratteristiche e vantaggi

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pittogrammi

Health hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Repr. 1B - STOT RE 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Effect of five anti-inflammatory steroids on collagen and glycoaminoglycan synthessis in vitro
Saarni H, et al.
British Journal of Dermatology, 103(2), 167-173 (1980)
V Salini et al.
International journal of immunopathology and pharmacology, 24(1), 211-216 (2011-04-19)
Relapses are frequently observed in subjects with chronic tendinopathies. Corticosteroid injections are usually performed with positive results, but are uncomfortable for the patient and not free from side effects. The aim of this pilot study is to evaluate the short-term
Annabel Maruani et al.
International journal of pharmaceutics, 395(1-2), 84-90 (2010-05-18)
Topical steroids are efficient in vasoconstriction potential, which is linked to their anti-inflammatory activity. Low-frequency ultrasound (US) applied on the skin (sonophoresis) may enhance the transdermal transport of various steroids. We aimed to assess, in a simple, blinded, randomized controlled
Yasutomo Fujii et al.
Archives of dermatological research, 302(9), 645-652 (2010-06-16)
Topical glucocorticoids, widely used for the treatment of a variety of dermatitises, are known to exacerbate atopic dermatitis after long-term or inappropriate use. In some animal models, topical glucocorticoids augment the allergic cutaneous inflammation after repeated application, suggesting a relationship
Feray Soyupek et al.
Rheumatology international, 32(10), 3229-3234 (2011-11-01)
Firstly, we aimed to determine the effectiveness of various treatment modalities using ultrasonography (US), and secondly, we aimed to assess the correlations between the ultrasonographic findings and electrophysiological tests, symptom severity, functional status and physical findings. 74 hands of 47

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