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Merck
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주요 문서

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D1069

Sigma-Aldrich

Desloratadine

powder, ≥98% (HPLC)

동의어(들):

8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine, Clarinex®, NSC 675447

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크기 선택

10 MG
₩367,735
50 MG
₩1,376,137

₩367,735

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청
모든 사진(1)

크기 선택

보기 변경
10 MG
₩367,735
50 MG
₩1,376,137

About This Item

실험식(Hill 표기법):
C19H19ClN2
CAS Number:
100643-71-8
Molecular Weight:
310.82
MDL number:
MFCD00871949
UNSPSC 코드:
12352200
PubChem Substance ID:
329798668
NACRES:
NA.32

₩367,735

구입 가능 여부는 고객센터에 문의하십시오.
벌크 견적 요청

분석

≥98% (HPLC)

양식

powder

solubility

DMSO: >10 mg/mL

저장 온도

2-8°C

SMILES string

Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1

InChI

1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2

InChI key

JAUOIFJMECXRGI-UHFFFAOYSA-N

유전자 정보

human ... HRH1(3269)

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애플리케이션

Desloratadine has been used to test its effect on embryoid body development in in vitro gastrulation model of P19C5 stem cells.[1] It has also been used as an antihistamine mimic in rats[2] and to treat lung cancer (A549) and glioblastoma (U87) cells in various cellular studies.[3]

생화학적/생리학적 작용

A non-sedating H1-receptor antagonist, free from antimuscarinic/anticholinergic effects. It has novel antiallergic and anti-inflammatory effects.
Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects.

법적 정보

Clarinex is a registered trademark of Schering Corp.

관련 제품

제품 번호
설명
가격

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

390.2 °F - Pensky-Martens closed cup

Flash Point (°C)

199 °C - Pensky-Martens closed cup

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시험 성적서(COA)

Lot/Batch Number
0000396280
0000396280
0000263326
0000235913
0000235913

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Oxidative Medicine and Cellular Longevity, 2019 (2019)
Translational Physiology: Prolonged intake of desloratadine: mesenteric lymphatic vessel dysfunction and development of obesity/metabolic syndrome
Gasheva OY, et al.
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Nicholas Cutrona et al.
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