1303501

Halothan

United States Pharmacopeia (USP) Reference Standard

• Synonym(e): 2-Brom-2-chlor-1,1,1-trifluorethan, Halothan
• Lineare Formel: BrCH(Cl)CF₃
• CAS-Nummer: 151-67-7
• Molekulargewicht: 197.38
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749984
• MDL number: MFCD00009602
• Beilstein/REAXYS Number: 1736947

Eigenschaften

• grade: pharmaceutical primary standard
• agency: USP
• vapor pressure: 4.5 psi ( 20 °C)
• API family: halothane
• manufacturer/tradename: USP
• refractive index: n20/D 1.369 (lit.)
• bp: 50.2 °C (lit.)
• density: 1.872 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(Cl)Br
• InChI: 1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H
• InChI key: BCQZXOMGPXTTIC-UHFFFAOYSA-N
• Gene Information: human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879), GLRA1(2741), GLRB(2743), KCNK10(54207), KCNK18(338567), KCNK2(3776), KCNK3(3777), KCNK9(51305)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Halothane USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

2-Brom-2-chlor-1,1,1-trifluorethan ist ein Inhalationsanästhetikum. In einer Wirkung, die als unabhängig von der Anästhesie erachtet wird, hemmt Halothan die Synthese von 5-Hydroxytryptamin in Hirngewebe, wahrscheinlich im Tryptophanhydroxylase-Schritt.

Inhalationsanästhetikum

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H315,H318,H335,H360
• Hazard Classifications: Eye Dam. 1 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pcodes: P202 - P261 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313