GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
Synonyms:
ECA4, EJM, EJM5
Species:
Human GABRA1 (2554), Mouse Gabra1 (14394), Rat Gabra1 (29705), domestic guinea pig Gabra1 (100721626), cow GABRA1 (780973), dog GABRA1 (489143), naked mole-rat Gabra1 (101719179), Zebrafish gabra1 (768183), sheep GABRA1 (101117759), chicken GABRA1 (374214)
UniProtKB ID:
Gene ID:
- Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Zolpidem solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Zolpidem for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GABRA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, rabbit
Application
western blot
Anti-GABA (No Gluteraldehyde) Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
immunohistochemistry
Anti-GABRA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-GABA A Receptor α1 chain Antibody, NT, clone BD24, clone BD24, Chemicon®, from mouse,
Species Reactivity
avian, bovine, human, pig
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-GABA A Receptor β2/3 Antibody, clone 62-3G1, Upstate®, from mouse,
Species Reactivity
bovine, human, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Product Number
Description
Species
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species
Phenol, puriss., meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (GC),
Species
human