I5161

Jodacetamid

• Lineare Formel: ICH₂CONH₂
• CAS-Nummer: 144-48-9
• Molekulargewicht: 184.96
• EC Number: 205-630-1
• UNSPSC Code: 12352202
• NACRES: NA.21
• Beilstein/REAXYS Number: 1739080
• MDL number: MFCD00008028

Eigenschaften

• biological source: synthetic
• Quality Segment: 400
• assay: ≥99% (NMR)
• form: powder
• mp: 92-95 °C (lit.)
• solubility: H₂O: 0.5 M, clear, colorless
• suitability: suitable for manufacturing use
• storage temp.: 2-8°C
• SMILES string: NC(=O)CI
• InChI: 1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)
• InChI key: PGLTVOMIXTUURA-UHFFFAOYSA-N

Beschreibung

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

Biochem/physiol Actions

Iodacetamid dient als Alkylierungsreagens für Cysteinreste bei der Peptidsequenzierung. Es ist ein irreversibler Inhibitor von Enzymen mit Cystein im aktiven Zentrum. Mit Histidinresten reagiert es sehr viel langsamer, aber diese Aktivität ist für die Hemmung der Ribonuklease verantwortlich.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H317,H334,H413
• pcodes: P261 - P264 - P273 - P280 - P301 + P310 - P302 + P352
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: Not applicable
• flash_point_c: Not applicable